Polycystic Ovary Syndrome

ISBN-13: 9780824707460 / Angielski / Twarda / 2002 / 396 str.

Opis

Polycystic Ovary Syndrome discusses

the use of animal models in the study of PCOS

the occurrence of ovarian and adrenal abnormalities, cardiovascular risks, abnormal insulin secretion, and endothelial dysfunction in PCOS

modern therapeutic modalities, such as manipulation of diet and lifestyle, metabolic phenotyping, and treatment of hyperandrogenism

the effect of PCOS on long-term health
Exploring the direct and indirect effects of PCOS in each stage of life, from puberty and adolescence to adulthood, Polycystic Ovary Syndrome is an in-depth and illuminating source for obstetricians and gynecologists; medical, reproductive, and pediatric endocrinologists; practitioners in family, internal, and pediatric medicine; epidemiologists; developmental biologists and toxicologists; and scientists and medical students in these disciplines.

Spis treści

Overview

Historical Perspectives
Joseph W. Goldzieher

Epidemiology of Polycystic Ovary Syndrome

Are Women with Polycystic Ovary Syndrome at Risk for Cardiovascular Disease?
David S. Guzick and Evelyn O. Talbott

Polycystic Ovary Syndrome and Long-Term Disease Risks
Caren G. Solomon
Premature Pubarche, Insulin Resistance, and Adolescent Polycystic Ovary
Silva A. Arslanian and Selma Witchel

Reproductive Abnormalities

Morphological and Physiological Correlates of the Polycystic Ovary
Gregory F. Erickson and Shunichi Shimasaki

Ultrasound Examination of Polycystic and Multifollicular Ovaries
Didier Dewailly, Robert Yann, Christophe Lions, and Yves Ardaens

Adrenal Androgen Excess in Polycystic Ovary Syndrome
Ricardo Azziz

Neuroendocrine Dysfunction in Polycystic Ovary Syndrome
John C. Marshall, Christine A. Eagleson, and Christopher R. McCartney

Animal Models of Polycystic Ovary Syndrome

A Transgenic Mouse Model of Functional Ovarian Hyperstimulation: Implications for Polycystic Ovary Syndrome
Gabe E. Owens and John H. Nilson

Prenatal Androgen Excess Programs for Polycystic Ovary Syndrome in Female Rhesus Monkeys
David H. Abbott, Joel R. Eisner, Ricki J. Colman, Joseph W. Kemnitz, and Daniel A. Dumesic

Metabolic Abnormalities and Their Relationship to Polycystic Ovary Syndrome

Regulation of Metabolism and Reproduction Through the Insulin Receptor Substrat Protein Signaling System
Deborah J. Burks and Morris F. White

Molecular Mechanisms of Insulin Action in Polycystic Ovary Syndrome
Andrea Dunaif

Glucose Intolerance in Polycystic Ovary Syndrome: Role of the Beta Cell
David A. Ehrmann

Oligocentric Systems Associated with Central Obesity and Insulin Resistance: Models for Polycystic Ovary Syndrome
John D. Brunzell

Polycystic Ovary Syndrome and Coronary Vascular Disease: The Evidence?
Robert A. Wild

Vascular Function in Polycystic Ovary Syndrome
Helmut O. Steinberg, Giancarlo Paradisi, Marguerite K. Shepard, and Alain D. Baron

Genetics and Environmental Influences

The Genetics of Polycystic Ovary Syndrome: A Model for the Analysis of Complex Genetic Diseases
Margrit Urbanek, Deborah A. Driscoll, Jerome F. Strauss, III, Richard S. Spielman, Xinqi Wu, Andrea Dunaif, and Richard S. Legro

Role of Genes Encoding Steroidogenic Enzymes in Polycystic Ovary Syndrome
Stephen Franks, Neda Gharani, and Mark McCarthy

The Role of Obesity in Polycystic Ovary Syndrome
Ann E. Taylor

Dyslipidemia in Polycystic Ovary Syndrome: Etiology and Response to Treatment
Richard S. Legro

Environmental Factors in Polycystic Overy Syndrome: Are There Plausible Cause-and-Effect Hypotheses?
Claude L. Hughes, Ruchi Mathur, and David Geller

Intervention/Prevention Strategies

Lifestyle Factors and Polycystic Ovary Syndrome
Robert J. Norman and Michael J. Davies

Treatment of Hyperandrogenism
Rogerio A. Lobo

Ovulation Induction: Predictors of Ovarian Response and Clinical Outcomes
Babek Imani, Marinus J. C. Eijkemans, J. Dik F. Habbema, Bart C. J. M. Fauser, and Egbert R. te Velde

Diagnostic Criteria

Polycystic Ovary Syndrome: Diagnostic Criteria
R. Jeffrey Chang

Index

O autorze

R. Jeffrey Chang, Jerrold J. Heindel, Andrea Dunaif