Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth

ISBN-13: 9781468480313 / Angielski / Miękka / 2013 / 443 str.

Frederick Crane

Opis

The objective of this workshop was to examine the nature of plasma membrane electron transport and how this electron transport contributes to growth of cells. The workshop came at a time when the study of the plasma membrane oxidoreductase activity was beginning to attract more widespread attention from researchers working with both plants and animals. The rapid response of c fos and c myc Proto-oncogene to stimulation of plasma membrane redox activity by external oxidants under- scores a potential role of plasma membrane oxidoreductases in growth control. Other experiments with isolated endosomes in- dicate emerging roles in endocytosis and lytic processes. Primary attention was focused on trans plasma membrane electron transport which brings about the oxidation of cytosolic, NADH, NADPH or other substrates by electron flow across the plasma membrane to external oxidants including ferric iron, semide- hydroascorbate or oxygen. A major theme in the workshop was the relation of this electron flow to pH changes of the cytoplasm or the transfer of protons to the external medium. The presence and role of other oxidoreductases in the plasma membrane was documented, especially in regard to peroxide production. In plant cells this may contribute to cellular defense against invading para- sites. A corresponding function in animals has been long known and extensively discussed but was beyond the scope of this workshop.

Spis treści

Introductory Remarks.- Modulation of Redox Reactions Involved in DNA Synthesis by Oxygen and Artificial Electron Acceptors.- Redox Agents which Modulate the Growth of Melanoma Cells: Evaluation of Mechanisms.- Possible Role of Transplasma Membrane Ferricyanide Reductase in Mitogenic Activation of Rat Liver Cells.- The Requirement for Transmembranal Electron Flow for Cell Profiferation.- Roles for Plasma Membrane Redox Systems in Cell Growth.- Redox Components in the Plant Plasma Membrane.- Reduction-Oxidation Activities of Plant Plasmamembranes.- Purification of NADH-Ferricyanide and NADH-Duroquinone Reductases from Maize (Zeamays L.) Root Plasma Membranes.- The Turbo Reductase in Plant Plasma Membranes.- Specific Interaction of the Herbicide Sethoxydim with the Plasmalemma Redox System of Plant Cells.- NADH or NADPH?.- Mechanism and Control of Iron Uptake by Erythroid and Non-Erythroid Cells.- The Release of Iron from a Subfraction of Rat Liver Highly Enriched in Endosomal Organelles Requires both a Functional H+-ATPase and NADH.- Uptake of Iron from Ferric Iron Compounds by Isolated Hepatocytes.- Hepatocyte Iron Uptake — A Plasma Membrane Process or An Endosomal Process?.- Reductive Release of Iron from Transferrin and Receptor Mediated Recycling.- Transplasma Membrane Electron Transport Functions as A Ferric Reductase.- Modulation of Transferrin Receptor Gene Expression by Peptide Growth Factors and Role of the Receptor in Human Fibroblasts.- Basic and Clinical Studies of Transferrin-Adriamycin Conjugates: Mechanisms for a New Approach to Drug Targeting.- Control of Transplasma Membrane Diferric Transferrin Reductase by Antitumor Drugs.- A General Introduction to The Link Between Redox Reactions and Proton Gradients.- Regulation of Proton Diffusion Pathways in Chloroplast Thylakoids by Ca++ Gating.- Energy-Dependent Transport of Urate and Xanthine in the Unicellular Green Algae Chlamydomonas reinhardtii.- Mechanisms of Ion Transport in Plants: K+ as an Example.- Electron Transport at the Plasma Membrane and ATP-Driven H+ Extrusion in Elodea densa Leaves.- The Relationships Between Ferricyanide Reduction and Associated Proton Efflux in Mechanically Isolated Photosynthetically Competent Mesophyll Cells.- The Ferricyanide-Driven Redox System at the Plasmalemma of Plant Cells: Origin of the Proton Production and Reappraisal of the Stoichiometry of e?/H+.- Ferricyanide Changes the Transport Properties of Lamprothamnium Papulosum Plasmalemma.- b-Type Cytochromes, Light- and NADH-Dependent Oxido-Reductase Activities in Plant Plasma Membranes.- Kinetics of Redox State as Related to Plant Growth and Development.- Regulation of Transplasmalemma Electron Transport by Calcium and Light in Oat Mesophyll Cells.- Thioredoxin and Glutaredoxin: Functions in Growth-Dependent DNA Synthesis and Cellular Regulation via Thiol Redox Control.- Cytochrome b561 and the Maintenance of Redox Poise in Secretory Vesicles.- The Retinoic Acid-Induced Cascade of Events Leading to Granulocyte Differentiation in HL60 Through a Postulated GTP-Regulated Inducing Molecule.- Changes in Plasmalemma Functions Induced by Phytopathogenic Bacteria.- On the Occurrence of Oxidoreductases in the Apoplast of Leguminosae and Gramineae and Their Significance in the Study of Plasmamembrane-Bound Redox Activities.- Relationship between NAD+/NADH Levels and Animal Cell Growth.- Redox Control of Glutathione and Thioredoxin Reductases.- Cardiac Ca2+ Channels and Sarcolemma Redox.- Role of Na+/H+-Antiporter in Growth Stimulation by Ha-ras.- Protein Kinase C: Plasma Membrane to Nucleus.- Plasma Membrane Cytochrome Components: Midpoint Redox Potentials, Light- and NADH Mediated Reductions.- Localisation of Donor and Acceptor Sites of NAD(P)H Dehyrogenase(s) Using “Inside-Out” and “Right-Side Out” Plant Plasma Membrane Vesicles, and Characterization of Plasma Membrane-Bound b-Cytochromes.- NADH-Ferricyanide Oxidoreductase Activity in Maize Root Cell Plasma Membrane.- The Effect of Sethoxydim on the NAD(P)H Oxidation Associated With Isolated Plasmalemma Vesicles.- The Resolution of Two Phases of Ferricyanide Reduction in Cultured Carrot Cells.- Modification of Plasma Membrane DT-Diaphorase Activity Upon Transformation. A Comparison Between Astrocytes in Primary Culture and C6 Glioblastoma Cells.- Transplasma-Membrane Redox System in Erythrocyte Ghosts.- Stimulation of NADH-Cytochrome c Oxidoreductase of Endoplasmic Reticulum Transitional Elements by Retinol.- NADH-Dehydrogenases in Synaptic Plasma Membranes.- Are Plasmalemma Redox Protons Involved In Growth Control by Plant Cells?.- Is the Proton Extrusion Coupled to Ferricyanide Reduction Mediated by the H+-ATPase?.- Relationship of Plasma Membrane Redox Activity to Proton Transport in Roots of Iron-Deficient Cucumber.- Intracellular pH Modifications Linked to the Activity of the Ferricyanide Driven Activity of the Plasmalemma Redox System in Elodea densa Leaves, Acer pseudoplatanus and Catharanthus roseus Cells.- Preliminary Evidence for A Regulation of the Plasma Membrane Redox Chain by the Activity of the ATP-Driven H+ Pump in Elodea densa Leaves.- Relationship Between Auxin-Dependent Proton Extrusion and Plasmalemma Redox System in Maize Coleoptile Segments.- Possible Exploitation of an H+ Related Mechanism in the Treatment of Breast and Colon Tumors: A New Approach to the Adjuvant Treatment of Cancer.- Control of Sodium/Proton Exchange by Plasma Membrane Electron Transport.- Nitrate Uptake by Intact Sunflower Plants.- Metabolic Changes Associated With Ferricyanide Reduction by Elodea Leaves.- Stimulation of c-fos and c-myc Proto-Oncogene Expression by Ferricyanide, An Extracellular Electron Acceptor.- Effects of PMA on Protein Kinase C in Perfused Rat Heart.- Role of Zinc in Plasma Membrane Integrity and O2?-generating NADPH Oxidase Activity.- Anion Superoxide and Hydrogen Peroxide Formation Elicited by NAD(P)H Oxidation in Radish Plasmalemma Vesicles.- Ascorbate Free Radical Involvement in Elongation-Related Growth Processes in Onion Roots.- Role of Cell Surface on NADH-MDHA-Oxidoreductase: Lectin Inhibition.- Iron Reduction by Sunflower Roots Under Iron Stress.- Iron-Stress in Tomato (Lycopersicum esculentum cv. Rutgers) Results in Increased Iron Reduction on the Root Plasma Membrane.- Author Index.