Plant-Derived Anticancer Drugs in the OMICS Era: Biosynthesis, Function, and Applications

ISBN-13: 9781774912652 / Angielski

Deepu Pandita;Anu Pandita

Opis

The current anti-cancer synthetic medicines are inefficient and unsafe. The plants-based lead molecules such as taxol, camptothecin, podophyllotoxins, vinblastine, vincristine, homoharringtonine and numerous other anticancer compounds from Nature's arsenal are potentially safe and powerful alternative means that effectively fight against cancer. The volume looks at a variety of medicinal plants and approaches that have beneficial results against cancer. Topics include Unani approaches of anticancer plants, genetic engineering and CRISPR/CAS-mediated editing to enhance anticancer potential, computational approaches used in anticancer plants, and more. The volume also examines the metabolomics of plants that give them anti-cancer properties. This volume, Plant-Derived Anticancer Drugs in the OMICS Era: Biosynthesis, Function, and Applications, will be valuable to cancer researchers and drug developers among others.

Spis treści

1. Evaluation of Extracts from Curcu malonga and Zingiber officinale as Growth Inhibitors of HeLa and HuH-7 Cell Lines 2. Role of Herbal Medicines in Liver Cancer 3. Unani Approaches of Anticancer Plants Against Cancer 4. Exploration of Anticancer Medicinal Plants of Northern Hemisphere 5. Genetic Engineering of Plants for Enhanced Anticancer Potential 6. Genetic Engineering of Plants of Enhancing Secondary Metabolites with Anti-Cancerous Properties 7. Genomics of Plants with Anticancer Properties: Breaking New Ground in Cancer Therapy 8. Metabolomics of Anti-Cancer Plants 9. Computational Approaches Used in Anticancer Plants 10. CRISPR/CAS-Mediated Editing of Anticancer Plants 11. Zinc Finger Nuclease (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs): Based Genome Editing in Enhancement of Anticancer Activity of Plants

O autorze

Deepu Pandita is a Senior Lecturer in the Government Department of School Education, Jammu, India. She has more than 19 years of teaching experience. She has published editorials, book chapters, reviews, and research articles in journals of national and international repute and also acts as a reviewer, associate editor, and editor of several international journals. She has presented her research at professional conferences and has received awards for her work.

Anu Pandita is a Dietician at Vatsalya Clinic, Krishna Nagar, New Delhi, India. Previously she worked as a lecturer at Bee Enn College of Nursing, Talab Tillo, Jammu, India, and as a Dietician at Ahinsa Dham Bhagwan Mahavir Charitable Health Centre, New Delhi, India. She conducted a case study at the Pediatric Gastroenterology Ward at Nehru Hospital, PGI, Chandigarh, India, on a patient suffering from chronic liver disease. She has published books, book chapters, and research articles in journals of national and international repute and has also presented her research at national and international conferences.

Titles of related interest from Deepu Pandita and Anu Pandita:

• Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling,

and Ingredients with Insulin Mimetic Activity

• Plant Transposable Elements: Biology and Biotechnology

• CRISPR/Cas-Mediated Genome Editing in Plants

• Antidiabetic Potential of Plants in the Era of Omics

• Potent Anticancer Medicinal Plants: Secondary Metabolite Profiling, Active Ingredients,

and Pharmacological Outcomes