Physical Activity, Dietary Calorie Restriction, and Cancer

ISBN-13: 9781461427513 / Angielski / Miękka / 2012 / 186 str.

Anne McTiernan

Opis

The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.

Spis treści

Chapter 1: Introduction Anne McTiernan, MD, PhD Rachel Ballard-Barbash, MD, MPH Linda Nebeling, PH.D., MPH, RD, FADA Chapter 2: Epidemiology of overweight/obesity and cancer risk Dr Andrew Renehan PhD FRCS Chapter 3: Epidemiology of physical activity and cancer risk. Becky Speck Kathryn Schmitz, PhD I-Min Lee, MD, ScD Anne McTiernan, MD, PhD Chapter 4: Dietary energy restriction, exercise, and mammary carcinogenesis Henry Thompson, PhD Chapter 5: Calorie restriction, exercise, and colon cancer prevention: a mechanistic perspective Connie Rogers, PhD Susan Perkins, PhD Steve Hursting, PhD Chapter 6: Mechanisms linking obesity to cancer risk in humans Ikuyo Imayama, MD, PhD, Caitlin Mason, PhD, Catherine Duggan, PhD Chapter 7: Mechanisms underlying the effects of physical activity on cancer Andrew Rundle, PhD Chapter 8: Physical activity, weight control, and cancer prognosis Kathryn Schmitz, PhD Melinda L. Irwin, PhD, MPH

Blurb

This book focuses on how obesity and sedentary lifestyles adversely affect cancer risk and survival for individuals as well as mechanisms that may underlie those associations. However, evidence is accumulating rapidly on the cost of obesity and sedentary lifestyles to society. For example, obesity is estimated to lead to costs of $147 billion in the US.6 While research on individual level interventions for weight loss and increasing physical activity have identified efficacious approaches, these changes in behavior are not maintained by many in the current environments in the US and worldwide that promote weight gain and inactivity. Research on environmental and policy approaches for addressing these problems at the societal level is needed7, 8 and is a major component of the President’s Report on Childhood Obesity released in April 2010. The epidemic of overweight and obesity and the increasing sedentary lifestyles will impact the magnitude and quality of the cancer problem globally. Increasing the knowledge of scientists, clinicians, and policy experts will aid in defining new prevention and treatment methods, to reduce the impact of energy balance on cancer, with the goal to eventually reduce the burden of cancer. Hopefully, this knowledge can be translated into incentives for the general public, persons at high risk, and cancer patients and survivors to increase physical activity, reduce excess weight, and maintain energy balance lifelong.