Pharmacological Evaluation of Poly herbal formulation on urolithiasis

ISBN-13: 9786204748870 / Angielski / Miękka / 140 str.

Jagdish Kakadiya; Utsav Jigneshbhai

Opis

Pharmacological evalution of anti-urolithiatic activity of an ayurvedic formulation Goumutradi Kshar in ethylene glycol induced urolithiasis in rats. 0.75% Ethylene glycol(EG) in drinking water for 28 days was used to induced urolithiasis in albino wister rats. Five groups (Normal Control, Disease Control, Preventive-225mg/kg, Treatment-225mg/kg, Treatment-150mg/kg) were taken & Six animals were taken in each group. An ayurvedic formulation Goumutradi Kshar was given 225mg/kg orally as prophylactic treatment & 225mg/kg & 150mg/kg orally as curative treatment. After completion of 28 days drug & EG treatment, 24hr urine, blood, kidney homogenate and kidney histopathology collections were done. It has been concluded that an ayurvedic formulation Goumutradi Kshar shows anti-urolithiatic acitivity in ethylene glycol induced urolithiasis in rats. It act as stone removal, as it inhibits crystal growth as well as it also decreased stone promoters level and increased stone inhibitor level. It has been also considered as potent diuretic since it increased urine volume in rats.

O autorze

Kakadiya, JagdishDr Jagdish L Kakadiya is an Academician and researcher in the domain of Pharmacy field more than 13 years. He is including as Advisory board member or Reviewer in national and international journals. He has published more than 50 research and review papers in national & international journals. He has 10 h-index and 10 i10 Index in Google Scholar.