Persister Cells and Infectious Disease

ISBN-13: 9783030252434 / Angielski / Miękka / 2020 / 295 str.

Kim Lewis

Spis treści

Chapter 1:  Evolution under antibiotic treatments: interplay between antibiotic persistence, tolerance and resistance 

Nathalie Q. Balaban and Jiafeng Liu

Chapter 2: Antibiotic persisters and relapsing Salmonella enterica infections

Peter W. S. Hill and Sophie Helaine

Chapter 3: The Biology of Persister Cells in E. coli

Alexander Harms

Chapter 4: Persister Formation and Antibiotic Tolerance of Chronic Infections

Kim Lewis and Sylvie Manuse

Chapter 5: Persister formation driven by TisB-dependent membrane depolarization

Bork A. Berghoff and E. Gerhart H. Wagner

Chapter 6: Toxin-antitoxin systems and persistence

Nathan Fraikin, Frédéric Goormaghtigh and Laurence Van Melderen 

Chapter 7: Nutrient depletion and bacterial persistence. 

Wendy W. K. Mok  and Mark P. Brynildsen

 

Chapter 8: Genetic determinants of persistence in Escherichia coli

Dorien Wilmaerts, Pauline Herpels, Jan Michiels, Natalie Verstraeten

Chapter 9: Persister resuscitation

Arvi Jõers, Marta Putrinš, Niilo Kaldalu, Hannes Luidalepp, Tanel Tenson

Chapter 10: Host-pathogen interactions influencing Mycobacterium tuberculosis persistence and drug tolerance 

Huiqing Zheng and Robert B. Abramovitch

Chapter 11: Drug susceptibility of individual mycobacterial cells

Maikel Boot & Hesper Rego

Chapter 12: Antimicrobial drug discovery against persisters

Wooseong Kim, Iliana Escobar, Beth Burgwyn Fuchs, and Eleftherios Mylonakis

O autorze

Professor Kim Lewis, Northeastern University Boston, Massachusetts, USA

Blurb

This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level.