Pericyte Biology in Disease

ISBN-13: 9783030169077 / Angielski / Twarda / 2019 / 355 str.

Alexander Birbrair

Spis treści

Chapter 1 -  Pericytes in cutaneous wound healing

Chapter 2 - Pericytes in glioblastomas: multifaceted role within tumor microenvironments and potential for therapeutic interventions

Chapter 3 – Pericytes in breast cancer

Chapter 4 - Pericytes in sarcomas and other mesenchymal tumors

Chapter 5 – Pericytes in metastasis

Chapter 6 – The role of pericytes in Amyotrophic Lateral Sclerosis

Chapter 7 – Pericytes in Alzheimer’s Disease: novel clues to cerebral amyloid angiopathy pathogenesis

Chapter 8 - Pericytes in Multiple Sclerosis

Chapter 9 - Pericytes in ischemic stroke

Chapter 10 - Pericytes in Hereditary Hemorrhagic Telangiectasia

Chapter 11 - Pericytes in primary familial brain calcification 

Chapter 12 - Pericytes in type 2 diabetes

Chapter 13 - Pericytes in atherosclerosis

Chapter 14 - Pericytes in chronic lung disease

Chapter 15 - Pericytes in muscular dystrophies

Index 

O autorze

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Blurb

This volume explores pericytes' roles under distinct pathological conditions, ranging from tumors, ALS, Alzheimer’s disease, Multiple Sclerosis, stroke, diabetes, atherosclerosis, muscular dystrophies and more. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology – Novel Concepts, Pericyte Biology in Disease presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cell biology and clinicians involved with these specific diseases.