Peptides

ISBN-13: 9781489940995 / Angielski / Miękka / 2013 / 489 str.

Alan A. Boulton; Glen B. Baker; Q. J. Pittman

Opis

Techniques in the neurosciences are evolving rapidly. There are currently very few volumes dedicated to the methodology - ployed by neuroscrentists, and those that are available often seem either out of date or limited in scope. This series is about the methods most widely used by modern-day neuroscientists and is written by their colleagues who are practicing experts. Volume 1 will be useful to all neuroscientists since rt concerns those procedures used routmely across the wrdest range of s- disciplines. Collecting these general techniques together in a single volume strikes us not only as a service, but will no doubt prove of exceptronal utrlitarran value as well. Volumes 2 and 3 describe current procedures for the analyses of amines and their metabolites and of amino acids, respectively. These collections will clearly be of value to all neuroscrentists working m or contemplating research m these fields. Similar reasons exist for Volume 4 on receptor binding techniques, since experimental details are provided for many types of hgand-receptor binding, including chapters on general prin- ples, drug discovery and development, and a most useful app- dix on computer programs for Scatchard, nonlinear, and compe- tive displacement analyses. Volume 5 provides procedures for the assessment of enzymes involved in neurotransmitter synthesis and catabolism. Volumes in the NEUROMETHODS series will be useful to neurochemists, -pharmacologists, -physiologrsts, -anatomrsts, psychopharmacologists, psychiatrists, neurologists, and chemists (organic, analytical, pharmaceutical, medicinal); in fact, everyone involved m the neuroscrences, both basic and clmical.

Spis treści

Posttranslational Processing of Peptide Precursors to Fragments.- Peptides.- Immunocytochemical Techniques in Peptide Localization.- In Vivo and In Vitro Studies on Peptide Release.- Functional Identification of Peptide Receptors.- Identification of Neuropeptide Receptors.- Biochemical Approaches to the Study of Peptide Actions.- Behavioral Tests.- Integrative Physiological Studies of Peptides in the Central Nervous System.- In Vivo Electrophysiological Techniques in the Study of Peptidergic Neurons and Actions.- In Vitro Preparations for Electrophysiological Study of Peptide Neurons and Actions.- Molluscan Model Systems for the Study of Neuropeptides.