Pediatric Sleep Medicine: Mechanisms and Comprehensive Guide to Clinical Evaluation and Management

ISBN-13: 9783030655761 / Angielski / Miękka / 2022

Gozal, David

Opis

This book provides comprehensive coverage of all aspects related to pediatric sleep and its associated disorders. It addresses the ontogeny and maturational aspects of physiological sleep and circadian rhythms, as well as the effects of sleep on the various organ systems as a function of development. 

Organized into nine sections, the book begins with a basic introduction to sleep, and proceeds into an extensive coverage of normative sleep and functional homeostasis. Part three then concisely examines the humoral and developmental aspects of sleep, namely the emerging role of metabolic tissue and the intestinal microbiota in regulation. Parts four, five, and six discuss diagnoses methods, techniques in sleep measurement, and specific aspects of pharmacotherapy and ventilator support for the pediatric patient. Various sleep disorders are explored in part seven, followed by an in-depth analysis of obstructive sleep apnea in part eight. The book concludes with discussions on the presence of sleep issues in other disorders such as Down syndrome, obesity, cystic fibrosis, and asthma. 

Written by recognized leaders in the field, Pediatric Sleep Medicine facilitates an extensive learning experience for practicing physicians who encounter specific sleep-related issues in their practice.

Spis treści

Section (1) Ontogeny, Phylogeny, and Normal Human Sleep

Section (2) Physiologic Regulation in Sleep and During Development

Cardiovascular

Respiratory

Endocrine

Metabolic  and thermoregulation

Immune function

Gastrointestinal

Section (3) Sleep Mechanisms: Developmental Aspects

Neuroanatomy

Circadian clocks and networks

NREM sleep

REM sleep

Humoral and other sleep promoting factors

Upper airway and motor control during sleep

Sleep homeostasis and sleep regulation

Respiratory control during sleep and wakefulness

Section (4) Measurement of Sleep

Survey tools and screening questionnaires

The pediatric patient with a sleep complaint- initial interview and diagnostic planning

Setting up a pediatric sleep lab

Technologies in the pediatric sleep lab: present and future (actigraphy, CO2, pulse transit time, spectral analysis of EEG, ECG, pulse arterial tonometry, etc…)

Imaging approaches

Laboratory tests in pediatric sleep medicine

The nocturnal polysomnogram – approaches to scoring and interpretation in infants and children

MSLT in children

Section (5) Defining normal in pediatric sleep – reference, normative values

Section (6) Pharmacotherapy Of Sleep Disorders In Children

 

Wake promoting agents

Somnogenic agents

Drugs which affect sleep

Section (7) Acute And Chronic Ventilatory Support In Children

Supplemental oxygen

CPAP

BiPAP

AVAP

Other

Section (8) Disorders of sleep

Insomnia and Insufficient Sleep

Apnea of Infancy, ALTE, and SIDS

Apnea of Prematurity

Obstructive Sleep Apnea

Disorders Of Respiratory Controls And Central Hypoventilation Syndromes

Disorders Of Excessive Sleepiness (Narcolepsy, Idiopathic Hypersomnia)

Circadian Sleep Disorders 

Section (7) Sleep in Other Disorders

Neuromuscular disorders

Asthma

Cystic fibrosis

Bronchopulmonary dysplasia

Down syndrome

Obesity

Sickle cell disease

Epilepsy

Autism spectrum disorder

ADHD

Manic depressive disorders

Prader-Willi Syndrome

Craniofacial Syndromes

Developmental delay

Post brain concussion

Diabetes 

O autorze

David Gozal, MD, MBA, PhD 

Department of Child Health

MU Women's and Children’s Hospital

Children’s Hospital Research Institute

University of Missouri

Columbia, MO, USA

Leila Kheirandish-Gozal, MD, MSc

Department of Child Health

Child Health Research Institute

University of Missouri

School of Medicine

Colombia, MO, USA