Pediatric Inflammatory Bowel Disease

ISBN-13: 9783031147432 / Angielski / Twarda / 2023 / 861 str.

Petar Mamula; Judith R. Kelsen; Andrew B. Grossman

Opis

The latest edition of this essential text provides a comprehensive overview of the unique pediatric issues of inflammatory bowel disease. Through new and thoroughly revised chapters, the volume features updates on all aspects of etiology, diagnosis, and treatment, with an emphasis on recent understanding of pharmacokinetics and the utilization of cutting edge therapeutic monitoring to maximize efficacy of medical management. The new edition also highlights newer, recently approved drugs, emerging therapies, and the most recent recommendations regarding post-operative management for patients who ultimately require surgery. Written by experts in the field, Pediatric Inflammatory Bowel Disease, Fourth Edition is a valuable resource for both pediatric and adult gastroenterologists involved in the care of children with inflammatory bowel disease. 

Spis treści

          Part 1 Etiology and Pathogenesis

1. Genetics of Inflammatory Bowel Diseases
2. Immunologic Regulation of Health and Inflammation in the Intestine
3. Cytokines and Inflammatory Bowel Disease
4. The Gut Microbiota and Inflammatory Bowel Disease
5. Immune Dysregulation Associated with Very Early-Onset Inflammatory Bowel Disease                        Part 2 Epidemiology and Clinical Features              
6. The Epidemiology of Pediatric Inflammatory Bowel Disease
7. The Natural History of Crohn Disease in Children
8. Natural History of Ulcerative Colitis in Children
9. Pediatric Inflammatory Bowel Disease – Unclassified
10. Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease
11. Liver Disease in Pediatric Inflammatory Bowel Disease
12. Growth Impairment in Pediatric Inflammatory Bowel Disease
13. Inflammatory Bowel Diseases and Skeletal Health
14. Puberty and Pediatric-Onset Inflammatory Bowel Disease
15. Classification of Pediatric Inflammatory Bowel Disease                                                                         Part 3 Diagnosis
16. The History and Physical Exam
17. Differential Diagnosis of Inflammatory Bowel Disease
18. Laboratory Evaluation of Inflammatory Bowel Disease
19. Fecal Markers in Inflammatory Bowel Disease
20. Radiologic Evaluation of Pediatric Inflammatory Bowel Disease
21. Endoscopy and Inflammatory Bowel Disease
22. The Pathology of Chronic Inflammatory Bowel Disease
23. Capsule Endoscopy in Pediatric Inflammatory Bowel Disease
24. Bone Health in Pediatric Inflammatory Bowel Disease                                                                           Part 4 Medical Therapy
25. 5-Aminosalicylate Therapy
26. Antibiotic Therapy
27. Nutritional Management of Inflammatory Bowel Disease
28. Corticosteroid Therapy
29. 6-Mercaptopurine Therapy
30. Methotrexate
31. Infliximab Therapy for Pediatric Crohn’s Disease and Ulcerative Colitis
32. Anti-TNF Therapies Other Than Infliximab for the Treatment of Pediatric Inflammatory Bowel Disease
33. Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease
34. New Non-anti-TNF-α Biological Therapies for the Treatment of Inflammatory Bowel Disease
35. Medical Treatment of Perianal Crohn’s Disease Fistulae Treatment of Perianal Crohn’s Disease
36. Treatment of Acute Severe Ulcerative Colitis
37. Dietary Therapies for Inflammatory Bowel Disease
38. Integrative Health Therapies for Pediatric IBD                                                                                       Part 5 Surgical Therapy
39. Management of Intraabdominal Complications of Inflammatory Bowel Disease
40. Surgical Management of Crohn Disease in Children
41. Surgical Treatment of Ulcerative Colitis
42. Postoperative Surveillance and Management of Crohn’s Disease
43. Perioperative Immunosuppression in Inflammatory Bowel Disease
44. Pouchitis and Pouch-Related Complications
45. Title to come                                                                                                                                           Part 6 Research
46. Clinical Indices for Pediatric Inflammatory Bowel Disease Research
47. Clinical Trials (Clinical Perspective)
48. Global Regulatory Industry Perspective of Clinical Trials                                                                       Part 7 Special Considerations
49. Infectious Complications of Pediatric Inflammatory Bowel Disease
50. Psychological Aspects of Inflammatory Bowel Disease in Children and Adolescents
51. Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease
52. Irritable Bowel Syndrome and Functional GI Disorders in Inflammatory Bowel Disease
53. Inflammatory Bowel Disease in Pregnancy
54. Pediatric Inflammatory Bowel Disease Care in Low and Middle-Income Countries
55. Immunizations in The Child with Inflammatory Bowel Disease
56. Colitis-Associated Cancers
57. Quality Improvement in Inflammatory Bowel Disease
58. Fostering Self-Management and Patient Activation
59. Advocacy for Pediatric Patients with Inflammatory Bowel Disease
60. Advocacy for Pediatric Patients with Inflammatory Bowel Disease
61. Transition from Pediatric to Adult Care

O autorze

Petar Mamula, MD

Division of GI, Hepatology & Nutrition 

The Children's Hospital of Philadelphia 

Professor of Pediatrics 

Perelman School of Medicine at the University of Pennsylvania 

Philadelphia, PA

USA

Andrew B. Grossman, MD

Division of GI, Hepatology & Nutrition 

Co-Director, Center for Pediatric Inflammatory Bowel Disease

The Children's Hospital of Philadelphia 

Associate Professor of Clinical Pediatrics 

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, PA

USA 

Robert N. Baldassano, MD

Division of GI, Hepatology & Nutrition 

Director, Center for Pediatric Inflammatory Bowel Disease 

The Children's Hospital of Philadelphia 

Professor of Pediatrics 

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, PA

USA

Judith R. Kelsen, MD

Division of GI, Hepatology & Nutrition 

The Children's Hospital of Philadelphia 

Assistant Professor of Pediatrics 

Perelman School of Medicine at the University of Pennsylvania

Philadelphia, PA

USA

Jonathan E. Markowitz, MD, MSCE, NASPGHAN-F

Pediatric Gastroenterology

Prisma Health Children’s Hospital–Upstate

Professor and Vice Chair for Academic Affairs

Department of Pediatrics

University of South Carolina School of Medicine–Greenville

200 Patewood Drive, A-140

Greenville, SC  29615

Petar Mamula, MD, is a board certified Pediatric Gastroenterologist and Director of the Kohl's GI Nutrition and Diagnostic Center at Children's Hospital of Philadelphia. He is also Co-Director of the Center for Digestive, Liver and Pancreatic Medicine, a CHOP/Penn collaborative program.

Andrew B. Grossman, MD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia. He is the co-director of CHOP's Center for Pediatric Inflammatory Bowel Disease.

Robert N. Baldassano, MD, is a Pediatric Gastroenterologist and Director of the Center for Pediatric Inflammatory Bowel Disease at Children’s Hospital of Philadelphia.

Dr. Baldassano’s research focuses on children who have inflammatory bowel diseases, and he oversees a large team of researchers at CHOP working to translate discoveries in the laboratory into direct patient care for children. One promising area of current research involves investigating the intestinal microbiomes of children with inflammatory bowel diseases.

Judith R Kelsen, MD, is Program Director of the Very Early Onset Inflammatory Bowel Disease (VEO-IBD) Clinic and an Attending Physician in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia.

Jonathan Markowitz, M.D, served on faculty at the Children's Hospital of Philadelphia for approximately 5 years before he joined Greenville Children's Hospital in 2006, where he has served as division chief of pediatric gastroenterology for the last 6 years. He is a clinical professor of pediatrics at USC School of Medicine-Greenville.

Dr. Markowitz' research interests include eosinophilic esophagitis and inflammatory bowel disease. He has authored numerous articles and has lectured nationally and internationally. He is co-editor of Eosinophilic Esophagitis and Pediatric Inflammatory Bowel Disease. Dr. Markowitz has been featured in local and national media.