Pediatric Bone Sarcomas: Epiphysiolysis Before Excision

ISBN-13: 9780857295170 / Angielski / Miękka / 2011 / 152 str.

Jose Canadell; Mikel San-Julian; Jos Ca Adell

Opis

Sparing of the growth plate is an early feature of diaphyseal and meta-diaphyseal osteosarcoma. Capitalising on this characteristic, Jose Canadell has developed an innovative technique to preserve the epiphysis while resecting primary bone malignancies lying adjacent to the growth plate of skeletally immature patients. Using external ? xation devices, controlled distraction of the epiphysis from the growth plate permits iatrogenic separation of the epiphysis from the affected region. Subsequent resection is enhanced by a safe distal margin and Canadell s local control rates attest to the success of the procedure as an oncologically sound technique. The Canadell technique has been developed through rigorous examination of the behaviour of osteosarcoma, as well as an interrogation of the best modalities for assessing tumour invasion of the growth plate. Combining an innovative treatment philosophy with a sound knowledge of the behaviour of osteosarcoma and basic bone and growth plate biology, as well as an extensive experience with ancillary investigations and adjuvant therapies, Canadell has developed a robust surgical technique for the management of a challenging tumour in selected patients. This book is the culmination of Canadell s endeavours over the last two decades. It traces the steps that he has taken to validate the safety and ef? cacy of the Canadell technique as we know it today."

Recenzje

From the reviews:

"This book details surgery for bone cancers in children. ... The audience includes bone tumor surgeons as well as any medical professionals interested in musculoskeletal oncology. The book describes the different ways bone sarcomas are treated. ... Clinical results and a section of questions and answers are presented. The radiographs and clinical photographs are of very good quality. The references are abundant and relevant. ... Biomedical libraries, bone oncologists, and bone tumor surgeons are strongly encouraged to purchase this important book." (Edward Abraham, Doody's Review Service, October, 2009)

"This book represents a summary of the work of Jose Cañadell at Pamplona on epiphysiolysis in malignant bone tumours. The book introduces the subject by discussing the treatment of paediatric bone tumours, the surgical options available and the role of the growth plate as a barrier to tumour spread. ... The book is very interesting and the technique is fascinating and well explained. ... it will make a good addition to libraries in bone tumour units ... ." (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 20, May, 2010)

Spis treści

Treatment of Pediatric Bone Sarcomas.- Molecular Biology of Pediatric Bone Sarcomas.- Surgical Options for Limb Salvage in Immature Patients with Extremity Sarcoma.- Location of Sarcomas Within Bone: The Growth Plate.- A Histological Study of the Barrier Effect of the Physis Against Metaphyseal Osteosarcoma.- Growth Plate Involvement in Malignant Bone Tumours: Relationship Between Imaging Methods and Histological Findings.- Imaging-Based Indications for Resection with Epiphyseal Preservation.- Conservation of the Epiphysis While Removing Metaphyseal Bone Tumours: Epiphysiolysis Before Excision.- Clinical Results.- Other Techniques for Epiphyseal Preservation.- Questions and Answers.

Blurb

Pediatric Bone Sarcomas: Epiphysiolysis before excision addresses malignant bone tumours by focusing upon physeal distraction (epiphysiolysis) before excision. This technique has long been used by the authors of this book in preserving the joint in metaphyseal bone tumours in children. They are subsequently now sharing their knowledge and experience with all those in the field of orthopedic surgery.

In the last 30 years, the outcome for patients affected by malignant bone tumours has improved dramatically. Better knowledge of the disease, improved imaging methods, new surgical techniques and particularly the advent of chemotherapy have brought about increasing success in this field.

Preserving the life of these patients 30 years ago was the only aim of physicians. Now, survival rates have increased and the new challenges posed to the surgeon are on preserving the limb and its function, whilst avoiding complications. 30 years ago joint preservation close to the bone tumour was unheard of. More recently, this is a desire and possible outcome common to everyone who treats these patients.

Targeted primarily towards orthopedic surgeons and pediatric oncologists this book will also be of interest to all those in the fields of orthopedics, oncology, pediatrics and surgery.