Patient-Specific Stem Cells

ISBN-13: 9780367868017 / Angielski / Miękka / 2020 / 280 str.

Deepak A. Lamba

Opis

An in-depth overview, this book covers the generation of Pluripotent stem cells (iPSCs)and the current research in various labs on how the technology is being used to study the diseases and identify novel treatments. It addresses three main areas: (a) various methods of reprogramming somatic cells to derive patients specific IPS Cells, (b) Gener

Spis treści

1. Human induced pluripotent stem cells: derivation











2. Human induced pluripotent stem cells: banking, and characterization














3. Genetic and Epigenetic considerations in iPSC technology














4. CRISPR-based genome engineering in human stem cells














5. Stem cells for Parkinson’s disease














6. Huntington’s Disease and Stem Cells














7. Applications of Pluripotent Stem Cells in the Therapy and Modeling of Diabetes and Metabolic Diseases














8. The Role of iPSCs in Disease Modeling: Gaucher Disease and Related Disorders














9. Role of induced pluripotent stem cells in urological disease modeling and repair














10. Induced Pluripotent Stem Cells – a Research Tool and a Potential Therapy for RPE-associated Blinding Eye Diseases














11. Modeling Neuro-Retinal Development and Disease in Stem Cells

O autorze

Deepak A. Lamba is an Assistant Professor at the Buck Research Institute on Aging, Novato, USA, an Affiliate Assistant Professor, at the University of Washington, Seattle, USA, and an Adjunct Faculty at the Leonard Davis School of Gerontology, University of Southern California, USA.