Parkinson's Disease--II: Aging and Neuroendocrine Relationships

ISBN-13: 9781468488951 / Angielski / Miękka / 2012 / 270 str.

C. E. Finch

Opis

These Proceedings emanate from the Second Tarbox Parkinson's Disease Symposium held February 2-4, 1978, at the SouthPark Inn in Lubbock, Texas. The Symposium was sponsored by the Tarbox Parkin- son's Disease Institute and the Department of Pharmacology and Therapeutics of the Texas Tech University School of Medicine at Lubbock. The First Symposium took place in October, 1976. The Second Tarbox Parkinson's Disease Symposium boldly brought together investigators at the cutting edge of aging and neuroendo- crine research and attempted to relate them to Parkinson's disease. Credit for the concept must go to the Program Chairman, Dr. David E. Potter. Once the plan was conceived the organizers relied heavily on the advice of Dr. Caleb E. Finch, whose counsel in developing the program was invaluable. The final verdict on the success of this daring venture must await the outcome of the publication of this Volume. Nevertheless, those in attendance could not fail but note the enthusiasm and excitement of the participants as their findings from the diverse disciplines of the neurological, aging, and endo- crine sciences converged. This in itself is testimony that the Sym- posium accomplished some degree of success. The Tarbox Parkinson's Disease Institute was established in 1973 with funds appropriated by the State of Texas and is dedicated to research, patient care, and education in Parkinson's disease and related neurological disorders. The Institute is named after Mr.

Spis treści

Invited Speakers.- Age-Dependent Changes in Central Dopaminergic and Other Monoaminergic Systems.- Age-Related Changes in Brain Catecholamines: A Synopsis of Findings in C57BL/6J Mice and Other Rodent Models.- Aging and Neurotransmitter Systems.- Heterogeneity of Polypeptide Hormones during Aging.- Some Neuroendocrine Aspects of Aging.- Peptides in Parkinson’s Disease.- Submitted Communications.- Influence of the Thyroid Gland on Ovarian Function in the Aging Rat.- Hypothalamic-Pituitary-Ovarian Interactions during Reproductive Senescence in the Rat.- Age-Related Changes in Penile Erections and Circulating Testosterone in Middle-Aged Male Rats.- Age Effects on the Hypothalamic-Pituitary-Gonadal Control System in the Rat.- An Endocrine Hypothesis of Brain Aging and Studies on Brain-Endocrine Correlations and Monosynaptic Neurophysiology during Aging.- Cyclic Nucleotides in Neuroendocrine Function.- Biogenic Amine-Stimulated Adenylate Cyclase and Spiroperidol-Binding Sites in Rabbit Brain: Evidence for Selective Loss of Receptors with Aging.- Relative Quantitation of Monoamine Histofluorescence in Young and Old Non-Human Primates.- Integrated Morphology of Neuronal Catecholamines and Neurophysin in the Aged Macaque.- Loss of Choline Acetyltransferase Activity in Normal Aging and Senile Dementia.