Pancreatic Disease: Basic Science and Clinical Management

ISBN-13: 9781852337117 / Angielski / Twarda / 2004 / 490 str.

Frcs C. D. Johnson; C. W. Imrie; Ed. Colin D. Johnson

Opis

Pancreatic Disease: Basic Science and Clinical Management summarises the state of the art in basic science and clinical management of pancreatic disease. This book provides a clear and up-to-date review of the advancing areas in clinical pancreatology and clinical research related to the pancreas. Written by leading experts in the field, this comprehensive review directs the interested reader towards important and current published source material. Covering all aspects of pancreatic disease, contributions are included from pancreatic surgeons and medical pancreatologists on pancreatic cancer, acute pancreatitis and chronic pancreatitis. Special features include a systematic review of the evidence for the use of gemcitabine in pancreatic cancer prepared for the National Institute of Clinical Excellence (NICE), the UK body charged with evaluating new drug treatment. Gemcitabine has FDA approval. There are several contributions dealing with the management of pancreatic neuroendocrine tumours. This book will be useful to gastroenterologists, internists and surgeons, and specialist clinicians with an interest in pancreatic disease. Trainees in medical and surgical pancreatology will find it a companion to supplement standard textbooks.

Spis treści

PANCREATIC TUMOURS Neuroendocrine Tumours 1. Epidemiology of Pancreatic Neuroendocrine Tumours Helen Doran, John P. Neoptolemos, Evelyn M.I. Williams, Robert Sutton 2. Quality of Life Issues in Metastatic Carcinoid/Neuroendocrine Tumours JK Ramage 3. Insulinoma: Diagnosis and Localisation D. Sandeman 4. GI Hormone Producing Tumours: Syndromes and Treatment Options Mary McStay, Martyn Caplin Pancreatic Cancer 5. Progress by Collaboration: ESPAC Studies Robert Sutton, Deborah D. Stocken, Janet A Dunn, Helen Hickey, Michael G.T. Raraty, Paula Ghaneh, John Buckels, Mark Deakin, Clement W. Imrie, Helmut Friess, Markus W. Büchler, John P. Neoptolemos 6. Gemcitabine: a Systematic Review Susan E Ward, Eva Morris, Nick Bansback Novel Alternatives to Chemotherapy in Advanced Disease 7. Farnesyl Protein Transferase as a Target For Anti-Cancer Drug Design Helgi van de Velde,Vanina Popova, Irina Mountian, Peter de Porre 8. Gastrin Antibodies Martyn Caplin 9. Gene Transfer Paula Ghaneh, Christopher M. Halloran, Eithne Costello, John P. Neoptolemos 10. Suicide Gene Therapy Amor Hajri Pancreatic Cystic Tumours 11. Pancreatic Cystic Lesions and Neoplasms M. Kosmahl, Günter Klöppel 12. Pancreatic Involvement in von Hippel-Lindau Disease Pascal Hammel, Benoît Terris, Valérie Vilgrain, Philippe Ruszniewski, Stéphane Richard 13. Intraductal Papillary Mucinous Tumours Christian Partensky, J.Y. Scoazec, B Napoléon, F. P Bernard, F. Berger, J. Dumortier CHRONIC PANCREATITIS 14. Endoscopic Ultrasound in the Diagnosis of Chronic Pancreatitis and Pancreatic Cancer Bernhard Glasbrenner, Stefan Kahl, Peter Malfertheiner 15. Natural Course of Chronic Pancreatitis Paul G. Lankisch 16. Autoimmune Pancreatitis Günter Klöppel, Matthias Löhr, Daniel Longnecker Pancreatic Stellate Cells 17. What’s New in Pancreatic Stellate Cell Biology? Minoti Apte, Jeremy Wilson 18. PancreaticStellate Cells and their Role in Fibrogenesis Max G Bachem, Alexandra Schmid-Kotsas, Thomas Gress, Marco Siech, Adolf Grünert 19. Factors Influencing Pancreatic Stellate Cell Phenotype and Cell Turnover David Fine, Fanny Shek Diabetes and Chronic Pancreatitis 20. Diabetes Mellitus in Chronic Pancreatitis David Malka 21. Pancreatic Exocrine Insufficiency in Diabetes Mellitus Jutta Keller, Peter Layer HEREDITARY PANCREATITIS AND GENETIC PREDISPOSITIONS 22. The Genetic Basis of Hereditary and Sporadic Pancreatitis Jane E. Creighton, Richard M. Charnley 23. Cytokines in Chronic Pancreatitis Mark Cartmell, Andrew Kingsnorth 24. Cytokine Gene Polymorphisms in Acute Pancreatitis Colin J. McKay, Anton Buter 25. Genetic Polymorphism, the Immune Response and Chronic Pancreatitis Adrian C. Bateman, W. Martin Howell 26. Xenobiotic Metabolising Enzymes in Pancreatitis Helena Tabry, K. Palmer, Colin D. Johnson 27. Trypsin Activation and Inhibition in Pancreatitis Markus M. Lerch, Manuel Ruthenbürger, Frank Ch. Mooren, Verena Hlouschek, Julia Mayerle, Peter Simon, F. Ulrich Weiss ACUTE PANCREATITIS Selecting Severe Acute Pancreatitis for Trials and for Treatment 28. Apache-II Mike Larvin 29. Enzymes and Activation Peptides Pauli A. Puolakkainen 30. Organ Failure Clement W. Imrie 31. Individual Features Related to Severity Colin D. Johnson Management of Necrosis in acute pancreatitis 32. Sterile Necrosis: Current Concepts and Management Strategies Shailesh Shrikhande, Helmut M. Friess, Jan Schmidt, Jens Werner, Waldemar Uhl, Markus W. Büchler 33. Management of Infected Pancreatic Necrosis Ross Carter 34. Antibiotics in Acute Pancreatitis Hans H. Beger, Rainer Isenman Enteral Nutrition in Acute Pancreatitis 35. Enteral Nutrition and the Role of the Mucosal Barrier Basil J. Ammori 36. Early Enteral Nutrition and Markers of the Inflammatory Response in Severe Acute