Pahs and Related Compounds: Biology

ISBN-13: 9783540634225 / Angielski / Twarda / 1997 / 388 str.

Alasdair H. Neilson; O. Hutzinger; A. H. Neilson

Opis

The volumes 3/I and 3/J present a modern account of polycyclic aromatic hydrocarbons (PAHs) and their heterocyclic analogs in the environment. The authors are internationally well recognized scientists belonging to those working presently in the frontline of the different subfields of this interdisciplinary area of environmental science; they give an integrated thorough overview on this hot topic. Extensive cross-referencing between chapters provides the readers with an easy access to all major areas. Due to the huge amount of material the text is published in two volumes (3/I and 3/J). It is expected that both volumes will soon become a major source of information and inspiration for all researchers actively working in PAH environmental chemistry or ecology.

Spis treści

A.H. Neilson and A.-S. Allard: Microbial Metabolism of PAHs and Heteroarenes.- E. Cavalieri and E. Rogan: Mechanisms of Tumor Initiation by Polycyclic Aromatic Hydrocarbons in Mammals.- R. Jankowiak and G.J. Small: Analysis of PAH-DNA Aduccts - Fluorescence Line-Narrowing Spectroscopy.- R. Ramanathan and M.L. Gross: Mass Specrometry Techniques: DNA Adducts of PAHs and Related Carcinogens.- T.C. van Brummelen, B. van Hattum, T. Crommentuijn and D.F. Kalf: Bioavailability and Ecotoxicity of PAHs.- G.-J. de Maagd and A.D. Vethaak: Biotransformation of PAHs and Their Carcinogenic Effects in Fish.- D. Delistraty: A Critical Review of the Application of Toxic Equivalency Factors to Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons in Mammals.

Blurb

The volumes 3/I (Chemistry) and 3/J (Biology) present diverse aspects of the environmental chemistry and ecology of PAHs and related compounds. Emphasis has been placed on a wide range of aspects not generally covered in other presentations. They cover not only basic aspects of the chemistry, analysis, sources, physico-chemical determinants of environmental distribution, and dissemination of PAHs, but also important areas such as heteroarenes, and PAHs produced from naturally occurring alicyclic precursors. Atmospheric degradation and transformation of PAHs are discussed as well as microbial metabolism of both PAHs and heteroarenes. Conventional and important new aspects of mammalian metabolism and the induction of cancer are presented, and the procedures used for demonstrating the structure of adducts involving PAH metabolites are discussed in detail.