PHOTOPHARMACOLOGY : Design & Applications

ISBN-13: 9786202521666 / Angielski

Mahavir Chhajed; Sumeet Dwivedi

Opis

The principle of photopharmacology is the introduction of a photoswitchable unit into the molecular structure of the bioactive compound itself. Dynamic control is achieved through addressing a small, photoresponsive molecule and, in a sense, is comparable to classical pharmacotherapy, making this method potentially interesting for medical applications. Specificity to the selected target is intrinsic to this approach, as it employs a highly optimized design of a selective, bioactive compound, into which a responsive element is introduced. Photopharmacological treatment is especially suitable in situations where the disease is localized. Action on exposed parts, such as the skin or eyes, seems the most natural target. However, the advances in designing molecular photoswitches that respond to deeper-penetrating red light make it increasingly viable to treat other localized conditions, such as infections and solid tumors

O autorze

Chhajed, Mahavir
Dr. Mahavir Chhajed working as Professor & Principal and Dr. Sumeet Dwivedi working as Professor & Head, Oriental College of Pharmacy & Research, Oriental University, Indore, (M.P.), India.They have keen interest in Biological screening of drugs, Pharmacological screening of drugs and Molecular design.