Oxidative stress and antioxidants in oral squamous cell carcinoma

ISBN-13: 9783843371711 / Angielski / Miękka / 2010 / 100 str.

Sridharan, Gokul

Opis

Increased oxidative stress as a result of excessive production of lipid peroxidation and reactive nitrogen species in association with disturbances in antioxidant defense system have been implicated in the pathogenesis of several diseases, most notably oral cancer. Thus, estimation of oxidant antioxidant status in oral squamous cell carcinoma patients could serve as a useful marker in choosing the correct therapy and also to monitor the effectiveness of such therapy and tumor recurrence. Also antioxidant therapy might prove useful in preventing the adverse effects caused by chemotherapy and radiotherapy.As free radicals are considered to be involved in the development of pre-cancer, determination of oxidant-antioxidant status in these patients may be helpful in successful management, thereby arresting it in early stages and avoiding the possible consequences of progression to malignancy.

O autorze

Sridharan, GokulDr. Gokul S, MDS, currently serves as a lecturer (AssistantProfessor)in the department of oral pathology and microbiology atRajah Muthiah Dental College and Hospital, Annamalai University,Tamilnadu. He received his MDS degree from S.D.M College ofDental Sciences, Karnataka. He has several internationalpublications to his credit.