This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals.
Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protozoan and helminth infections focusing primarily on initial and subsequent resistance to treatment. The book closes with a discussion on the potential solutions of innovative therapy including new delivery mechanisms, broad-spectrum antibiotics, phytocompounds, and biofilms. Chapters feature magnified, microscopic photos for identifying structures as they appear on the skin.
Part of the Updates in Clinical Dermatology series, Overcoming Antimicrobial Resistance of the Skin is an important resource relevant during the COVID-19 pandemic, and is written for all medical healthcare professionals.
Section 1: Emerging Bacterial Resistance to Antibiotics
Chapter 1: Mechanisms of Bacterial Resistance
Chapter 2: Emerging Bacterial Infections
Chapter 3: Reemerging Bacterial Infections
Section 2: Emerging Resistance to Antivirals
Chapter 4: Mechanisms of Non-retroviral Resistance
Chapter 5: Mechanisms of Retroviral Resistance
Chapter 6: Emerging Viral Infections
Chapter 7: Reemerging Viral Infections: Implications of Lack of Vaccination
Section 3: Emerging Resistance to Antifungals
Chapter 8: Mechanisms of Antifungal Resistance
Chapter 9: Emerging and Reemerging Fungal Infections
Section 4: Emerging Resistance to Drugs for Protozoan and Helminth Infections
Chapter 10: Mechanisms of Anti-Protozoan/Helminth Drug Resistance
Chapter 11: Emerging and Reemerging Protozoan/Helminth Infections
Section 5: Innovative Therapies on the Forefront
Chapter 12: Phage Therapy
Chapter 13: The Role of Biofilms
Chapter 14: New Classes of Broad-spectrum Antimicrobials
Chapter 15: Phytocompounds
Chapter 16: Summary
Stephen K. Tyring, MD, PhD
University of Texas Health Science Center
Center for Clinical Studies
Houston, TX
USA
Stephen Andrew Moore
Arlington Center for Dermatology
Arlington Research Center
Arlington, TX
USA
Angela Yen Moore, MD
Arlington Center for Dermatology
Arlington Research Center
Arlington, TX
USA
Omar Lupi, MD, MSc, PhD
Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Policlinica Geral do Rio de Janeiro (PGRJ)
Ibero Latin American College of Dermatology (CILAD) International League of Dermatological Societies (ILDS)
Brazil
This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals.
Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protozoan and helminth infections focusing primarily on initial and subsequent resistance to treatment. The book closes with a discussion on the potential solutions of innovative therapy including new delivery mechanisms, broad-spectrum antibiotics, phytocompounds, and biofilms. Chapters feature magnified, microscopic photos for identifying structures as they appear on the skin.
Part of the Updates in Clinical Dermatology series, Overcoming Antimicrobial Resistance of the Skin is an important resource relevant during the COVID-19 pandemic, and is written for all medical healthcare professionals.