Outcome Measures and Metrics in Systemic Lupus Erythematosus

ISBN-13: 9783030733025 / Angielski / Miękka / 2021 / 418 str.

Zahi Touma

Spis treści

Introduction: Metrics and Psychometric Properties

Domains Measured in Systemic Lupus

Measuring Disease Activity

Measuring Damage

Measurements in Lupus Clinical Trials

Application of Measurements in Clinical Practice

Patient-reported Outcomes in Lupus

Health-related Quality of Life in Lupus

Assessment of Cognitive Function in Lupus

Assessment of Depression and Anxiety in Lupus

Assessment of Fatigue and Pain in Lupus

Emerging Concepts in Lupus: Sleep, Frailty, and Others

Activities and Participation for Patients with Lupus.

O autorze

Zahi Touma, MD, PhD, FACP, FACR

Associate Professor of Medicine, University of Toronto

Clinician-Scientist, Rheumatology, University Health Network and Mount Sinai Hospital
Scientist, Krembil Research Institute

Cross-Appointed Faculty, Institute of Health Policy, Management and Evaluation

Associate Member, Institute of Medical Sciences

Adjunct Scientist, Institute for Work and Health 

Toronto, ON 

Canada

Blurb

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. 

This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.