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Section 1. Rotator Cuff Repair
1. Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair - Rush University Medical Center, Chicago, Illinois
2. Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears - Stanford University, Redwood City, California
3. Regenexx™ SD Versus Exercise Therapy for Rotator Cuff Tears - Centeno-Schultz Clinic, Broomfield, Colorado
4. Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff Tears - Sanford Orthopedics and Sports Medicine, Fargo, North Dakota & Sioux Falls, South Dakota
5. Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears - Arizona Research Center, Phoenix, Arizona, United States; Biosolution research, La Mesa, California, United States; Lotus Clinical Research, LLC, Pasadena, California, United States; (and 8 more locations...)
6. Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the
Supraspinatus Muscle Lesions - Petr Šmíd, Znojmo, Czech Republic, Czechia
7. Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair - U.O.C. 1a Divisione, Azienda Socio Sanitaria Territoriale Centro Specialistico Ortopedico, Traumatologico Gaetano Pini-CTO; Milano, Milan, Italy, IRCCS Policlinico San Donato , San Donato Milanese, Milan, Italy
8. Mesenchymal Stem Cells in Rotator Cuff Repair - Universidade de São Paulo, São Paulo, SP, Brazil
9. Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells - Weiliang Shen, Hangzhou, Zhejiang, China
10. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland
Section 2. Knee Osteoarthritis
1. Impact of Mesenchymal Stem Cells in Knee Osteoarthritis - University Hospital Cleveland Medical Center, Cleveland, Ohio, United States
2. Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES) - Andrews Institute, Gulf Breeze, Florida; The Emory Clinic, Atlanta, Georgia; Duke University, Durham, North Carolina; Sanford Health, Fargo, North Dakota; Sanford Health, Sioux Falls, South Dakota
3. Early Regenerative Intervention for Post-Traumatic Osteoarthritis (ERIPTO) - The Center for Primary Care and Sports Medicine, Aurora, Illinois, United States; Affinity Health Research Institute, Oak Brook, Illinois, United States; Genesis Orthopedics and Sports Medicine, Oak Brook, Illinois
4. Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction - The Steadman Clinic, Vail, Colorado
5. Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthritis – Advanced Orthoaedic Specialists, Fayetteville, Arkansas
6. The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis - Stanford University, Stanford, California, United States
7. A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells - Sanford Orthopedics and Sports Medicine, Sioux Falls, South Dakota
8. Stem Cell and Growth Factor Injury and Arthritis Clinical Research Study - Stone Research Foundation, San Francisco, California, United States
9. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland
10. Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis - Life Clinic, Warsaw, Mazovian, Poland
11. A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis (ADIPOA-2) - UH Montpellier, Montpellier, France
12. Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair (AURA) - Chapel Allerton Orthopaedic Centre, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom
13. Subchondral and Intra-articular Application of Bone Marrow Concentrate for Knee Unicompartmental OA (Marrow Mule) - Istituto Clinico Humanitas, Rozzano, Milano, Italy
14. Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells - Qilu hospital of Shandong University, Jinan, Shandong, China
15. Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis - Changhai hospital, Shanghai, China
16. Very Small Embryonic-like Stem Cells for Knee Osteoarthritis - Biological treatment center in Fuda cancer hospital, Guangzhou, Guangdong, China
17. Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis - China-Japan Friendship Hospital, Beijing, China; The Second Affiliated hospital of Zhejiang University School of Medicine, Hangzhou, China; Huashan Hospital Affiliated to Fudan University, Shanghai, China, (and 3 more locations...)
18. Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells (GXCPC1) for Knee Osteoarthritis - GWOXI Stem CellApplied Technology Co., Ltd., Hsinchu, Taiwan
19. Treatment of Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells - Yantai Yuhuangding Hospital, Yantai, Shandong, China
20. Clinical Study of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for Treatment of Knee Osteoarthritis - Liaocheng city people's hospital, Liaocheng, Shandong, China
21. Mesenchymal Stem Cell Transplantation for Osteoarthritis - Yantai Yuhuangding Hospital, Yantai, Shandong, China
22. Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury - Qilu hospital of Shandong University, Jinan, Shandong, China
23. Adipose-derived Stem Cells (ADSCs) for Knee Osteoarthritis - Taipei Veterans General Hospital, Taipei, Taiwan; Chang Gung Memorial Hospital Linkou, Taoyuan City, Taiwan
24. Allogeneic Bone Marrow MSC Therapy for Knee Osteoarthritis - Taipei Veterans General Hospital, Taipei, Taiwan
25. Evaluate Safety and Explore Efficacy of SMUP-IA-01 in Patients With Knee Osteoarthritis - Seoul National University Hospital, Seoul, Jongno-gu, Korea, Republic of
26. Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects, Adipose-derived mesenchymal progenitor cells - Shanghai ninth people's
hospital, Shanghai, Shanghai, China
27. Follow-up Study for Participants Jointstem Clinical Trial - KyungHee University Gangdong Hospital, Seoul, Korea, Republic of; GangNam Severance Hospital, Seoul, Korea, Republic of
28. A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis - Chungbuk National University Hospital, Cheongju-si, Korea, Republic of; Yeungnam University Hospital, Daegu, Korea, Republic of; Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of; (and 9 more locations...)
29. Follow-up Safety and Efficacy Evaluation on Subjects Who Completed Phase I Clinical Trial - Seoul national University Hospital, Seoul, Jongno-gu, Korea, Republic of Korea
30. Clinical Study of Intra Articular Injection of Catholic MASTER Cell (Bone Marrow Derived
Mesenchymal Stem Cell) in Knee Osteoarthritis (MSC-OA) - Catholic University of Korea, Seoul, Korea, Republic of
31. Follow-up Study for Participants of Jointstem Phase 3 Clinical Trial - Chungbuk National University Hospital, Cheongju-si, Korea, Republic of; Yeungnam University Hospital, Daegu, Korea, Republic of; Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of;
(and 10 more...)
32. Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection
of ADMSC Compared to Negative Control After High Tibial Osteotomy in the Osteoarthritis Patients. - KyungHee University, Gangdong Hospital, Seoul, Korea, Republic of
33. Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis - Second affiliated hospital, school of medicine, Zhejiang Uni., Hangzhou, Zhejiang, China
34. The Safety/Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-O) Therapy for Patients With Osteoarthritis - Xiangya Hospital Central South University, Changsha, Hunan, China
35. WHARTON JELLY ORIGINATED MESENCHIAL STEM CELL in GONARTHROSIS (WHAMKO) - Erciyes University Faculty of Medicine, Melikgazi, Kayseri, Turkey
36. Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis - Cell Therapy Center, Amman, Jordan
37. Use of Wharton Jelly Derived Mesenchymal Stem Cells for Knee Osteoarthrosis - Cell Therapy Center, Amman, Jordan
38. Effects of α MAT Versus Steroid Injection in Knee Osteoarthritis (STα MAT-knee Study)-
American University of Beirut Medical Center, Beirut, Lebanon
39. Implantation of Allogenic Mesenchymal Stem Cell From Umbilical Cord Blood for Osteoarthritis Management - Universitas Indonesia, Jakarta Pusat, Jakarta, Indonesia
40. Comparative Effectiveness of Arthroscopy and Non-Arthroscopy Using Mesenchymal Stem Cell Therapy (MSCs) and Conditioned Medium for Osteoartrithis (OA) - Gatot Soebroto Hospital
Jakarta Pusat, DKI Jakarta, Indonesia
41. The Evaluation of Safety and Effectiveness of Intraarticular Administration of
Autologous Stromal-Vascular Fraction of Adipose Tissue Cells for Treatment of Knee
Joint Arthrosis - Swiss Medica XXI Century S.A., Moscow, Russian Federation; IM Clinic, Belgrade, Serbia
42. Efficacy of Bone-marrow-derived and Placenta-derived Multipotent Mesenchymal Stem / Stromal Cells for Osteoarthritis - Institute of Cell Therapy, Kyiv, Ukraine
43. Bone Marrow Versus Adipose Autologous Mesenchymal Stem Cells for the Treatment of
Knee Osteoarthritis – Omnihospital, Guayaquil, Guayas, Ecuador
Section 3. Labral Repair
1. BMAC Use With Labral Repair - MGH, Massachusetts General Hospital, Boston, Massachusetts, United States
Jeffrey N. Weiss, MD
The Healing Institute
Margate, FL, USA
Jeffrey N. Weiss, MD is the former Chief of Retinal Surgery at the Joslin Diabetes Center in Boston, Faculty of Harvard Medical School, and Visiting Scientist at the Massachusetts Institute of Technology. He entered college at 16 years of age, and medical school at age 19 on full scholarships. While in medical school he obtained a degree in Electrical Engineering, Magna Cum Laude with distinction, and graduated from Medical School, Summa Cum Laude, at 23 years of age.
Dr. Weiss is the author of more than 100 publications, including 11 books, holds more than 20 U.S. and foreign patents, and has been a Reviewer for multiple scholarly journals. He has served as a Visiting Professor, performed surgery, and lectured nationally and internationally. Dr. Weiss is also the founder of two companies, Ocular Research Associates Inc., and Micron Ophthalmic, Inc. which have manufactured and sold Dr. Weiss’ inventions worldwide.
Dr. Weiss performed the first retinal stem cell surgery in the world in 2010 and is the Principal Investigator of The Stem Cell Ophthalmology Treatment Studies I/II, the largest retinal and optic nerve stem cell studies in the world, The Neurologic Stem Cell Treatment Study, The Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study, and The Alzheimer’s, Cognitive Impairment and Autism Treatment Study. The studies are Institutional Review Board (IRB) approved, registered with NIH and listed on ClinicalTrials.gov.
Dr. Weiss first visited Dubai in 2008, where equipment he had invented was being showcased at Arab Health, the second largest medical equipment meeting in the world. In 2015, he obtained a Dubai medical license and has been travelling to Dubai to examine patients, perform surgery and lecture. His work has been featured in all the major Dubai newspapers and television. He was a finalist for the United Arab Emirates HealthCare Award in 2018 and 2019.
This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials.
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