Organogenesis in Development: Volume 90

ISBN-13: 9780123809124 / Angielski / Twarda / 2010 / 456 str.

Koopman Cnd

Opis

Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians.

• Summarizes the key morphological and cellular events
• Emphasizes up-to-date research relating to molecular control mechanisms
• Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease
• Distils common themes and differences for comparative studies
• Highlights key remaining questions and sets the agenda for future research

Spis treści

1. How to Make a Heart: The Origin and Regulation of Cardiac Progenitor CellsSte´phane D. Vincent and Margaret E. Buckingham2. Vascular Development-Genetic Mechanisms and Links to Vascular DiseaseJohn C. Chappell and Victoria L. Bautch3. Lung OrganogenesisDavid Warburton, Ahmed El-Hashash, Gianni Carraro, Caterina Tiozzo, Frederic Sala, Orquidea Rogers, Stijn De Langhe, Paul J. Kemp, Daniela Riccardi, John Torday, Saverio Bellusci, Wei Shi, Sharon R Lubkin, and Edwin Jesudason4. Transcriptional Networks and Signaling Pathways that Govern Vertebrate Intestinal DevelopmentJoan K. Heath5. Kidney Development: Two Tales of TubulogenesisMelissa Little, Kylie Georgas, David Pennisi, and Lorine Wilkinson6. The Game Plan: Cellular and Molecular Mechanisms of Mammalian Testis DevelopmentElanor N. Wainwright and Dagmar Wilhelm7. Building Pathways for Ovary Organogenesis in the Mouse EmbryoChia-Feng Liu, Chang Liu, and Humphrey H-C Yao8. Vertebrate SkeletogenesisVe´ronique Lefebvre and Pallavi Bhattaram9. The Molecular Regulation of Vertebrate Limb PatterningNatalie C. Butterfield, Edwina McGlinn, and Carol Wicking10. Eye DevelopmentJochen Graw