Obesity and Diabetes

ISBN-13: 9781617376306 / Angielski / Miękka / 2010 / 555 str.

Christos S. Mantzoros

Opis

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.

Spis treści

Part I. History and Epidemiology Obesity and Diabetes: The Historical Events Marking the Evolution of the Understanding of the Pathophysiology and Treatment of Two Related Diseases George Karanastasis and Christos S. Mantzoros Epidemiology of Obesity and Diabetes: Prevalence and Trends Susanna C. Larsson and Alicja Wolk Part II. Genetics and Pathophysiology Genetics of Obesity and Diabetes Despina Sanoudou and Christos S. Mantzoros Nutrients and Peripherally Secreted Molecules in Regulation of Energy Homeostasis Greeshma K. Shetty, Diana Barb, and Christos S. Mantzoros Central Integration of Peripheral Signals in Regulation of Energy Homeostasis Greeshma K. Shetty, George Karanastasis, and Christos S. Mantzoros Role of Energy Expenditure in Regulation of Energy Homeostasis Eric S. Bachman Pathophysiology of Diabetes in Obesity Geetha R. Soodini and Osama Hamdy Part III. Diagnosis, Clinical Manifestations, and Complications Diagnosing Obesity, Diabetes Mellitus, and the Insulin Resistance Syndrome Diana Barb and Christos S. Mantzoros Metabolic Syndrome Rochelle L. Chaiken and Mary Ann Banerji Obesity, Diabetes, and Hypertension Anjanette S. Tan, Stephen A. Brietzke, David W. Gardner, and James R. Sowers Dyslipidemia Associated With Diabetes and Insulin Resistance Syndromes Jody Dushay and J. Peter Oettgen Obesity, Diabetes, and Endothelial Dysfunction Geetha R. Soodini, Edward S. Horton, and Osama Hamdy Atherosclerosis and Peripheral Vascular Disease: Sequelae of Obesity and Diabetes Satish N. Nadig and Allen Hamdan Obesity, Diabetes, and Risk of Cancer: A Review of Epidemiological Studies Susanna C. Larsson, Hans-Olov Adami, and Alicja Wolk Polycystic Ovary Syndrome and Its Metabolic Complications Emilia P. Liao and Leonid Poretsky Obesity and Type 2 Diabetes Mellitus in Childhood and Adolescence Susann Blüher and Wieland Kiess Diabetic Retinopathy Vassiliki Poulaki and Joan W. Miller Obesity and Renal Disease Ayman Geneidy and Richard Solomon Diabetic Peripheral Neuropathy Rachel Nardin and Roy Freeman The Diabetic Foot Thanh L. Dinh and Aristidis Veves Erectile Dysfunction Kenneth J. Snow Infections in Diabetes Mellitus Sotirios Tsiodras, Iosif Kelesidis, Christos S. Mantzoros, and Adolf W. Karchmer The HAART-Induced Metabolic Syndrome Sotirios Tsiodras, Theodoros Kelesidis, and Christos S. Mantzoros Part IV. Treatment Diet and Lifestyle in the Prevention and Management of Type 2 Diabetes Frank B. Hu Diet, Exercise, and Behavioral Treatment of Obesity George L. Blackburn Medical Approaches to Treatment of the Obese Patient George A. Bray and Donna H. Ryan Medical Treatment of the Obese Patient With Type 2 Diabetes Jean L. Chan, Christos S. Mantzoros, and Martin J. Abrahamson Surgical Treatment of Obesity and Diabetes Benjamin E. Schneider and Edward C. Mun Future Developments in the Area of Pharmacotherapy: Molecules in Early-Stage Preclinical Development and in Clinical Trials That May Affect Energy Homeostasis Diana Barb, Greeshma K. Shetty, and Christos S. Mantzoros Index

Blurb

The increasing prevalence of diabetes and obesity in western societies today makes these two diseases the leading epidemics of the 21st century. Closely linked with the development of serious complications, including cardiovascular disease and several malignancies, the morbidity and mortality associated with obesity and diabetes will continue to escalate as the population ages and becomes more sedentary. In Obesity and Diabetes, international experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.
Authoritative and up-to-date, Obesity and Diabetes offers a comprehensive review of the scientific and clinical aspects of obesity and diabetes, even while providing a powerful incentive to focus our public health efforts on prevention and our clinical efforts on treatment.