Section I. Introduction1. Introduction: Nutrition, the microbiome, and the epigenome in human health and disease
Section II. Diet, lifestyle and the microbiome in development and inflammatory diseases2. The microbiome across the lifecycle3. The microbiome in infant gut health and development4. The microbiome in early life as a risk factor for autoimmune diseases5. The microbiome in gut inflammation and carcinogenesis6. Obesity and the microbiome: A role for microbes in insulin resistance7. Fiber and the gut microbiome and its impact on inflammation8. Diet-specific impacts on the gut microbiome and their relation to health and inflammation9. Hypertension, Obesity, and the microbiome in cardiovascular disease10. Bariatric surgery, gut microbes, and metabolic health11. Caloric restriction in the microbial regulation of inflammaging12. Exercise, the gut microbiome and inflammatory disease
Section III. Nutrition and the epigenome in metabolic and cardiovascular diseases13. Obesity, histone acetylation and insulin resistance14. Obesity, DNA methylation and metabolic disease15. Diet, histone modifications and cardiovascular diseases16. Diet, DNA methylation and cardiovascular diseases17. Obesity and non-coding RNAs in epigenetic inheritance of metabolic disease18. Caloric restriction in the epigenetic regulation of aging and longevity19. Exercise in epigenetic programing throughout life
Section IV. Diet, epigenetics, and the microbiome in inflammatory disease20. Gut microbiome, epigenetics and neuro-inflammatory disease21. Caloric restriction, gut microbes, epigenetics and inflammaging22. Obesity, gut bacteria and the epigenetic control of metabolic disease23. The microbiome-epigenome axis in infant gut health and development24. The microbiome and epigenome intersect to regulate gut inflammation
Section V. Conclusions: Health-disparities in diet, epigenetics and gut microbes25. Race, gender and ethnicity in the control of our gut microbes26. The role for social-environmental influences in epigenetic determination27. Practical applications for diet and lifestyle to improve microbial and epigenetic health