Nutrition and Epigenetics

ISBN-13: 9781482203813 / Angielski / Twarda / 2014 / 422 str.

Emily Ho; Frederick Domann

Opis

Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text:

• Documents the epigenetic effect of antioxidants and their health benefits
• Adds to the understanding of mechanisms leading to disease susceptibility and healthy aging
• Illustrates that the epigenetic origins of disease occur in early (fetal) development
• Synthesizes the data regarding nutrient and epigenomic interactions

Nutrition and Epigenetics highlights the interactions among nutrients, epigenetics, and health, providing an essential resource for scientists and clinical researchers interested in nutrition, aging, and metabolic diseases.

Spis treści

Early-Life Exposures and the Epigenome: Interactions between Nutrients and the Environment. Maternal Diet and Exercise: Influences on Obesity and Insulin Resistance. Maternal Protein and Fat Intake: Epigenetic Consequences on Fetal Development. Folate, DNA Methylation, and Colorectal Cancer. Parental Nutrition, Epigenetics, and Chronic Disease. Alcohol and DNA Methylation. Ascorbate as a Modulator of the Epigenome. Epigenetic Regulation of Cellular Responses toward Vitamin D. Role of Iron in Epigenetic Regulation of Gene Expression. Selenium and Epigenetic Effects on Histone Marks and DNA Methylation. Proline: Metabolic Sensing and Parametabolic Regulation. Dietary Effects on Adipocyte Metabolism and Epigenetics. Epigenetics of BRCA-1–Related Breast Tumorigenesis and Dietary Prevention. Regulation of Histone Acyltransferases and Deacetylases by Bioactive Food Compounds for the Prevention of Chronic Diseases.