Nutriose-Eudragit Coated Pellets For Colon Targeted Drug Delivery : A Novel Approach

ISBN-13: 9786202052931 / Angielski / Miękka / 2017 / 124 str.

Ashu Mittal; Debaprasad Ghosh; Pravin Kumar Singh

Opis

Multiparticulate drug delivery systems are consists of multiple small discrete units. They are mainly oral dosage forms. Each individual small discrete unit exhibit same desired characteristics. In the multiparticulate systems, the dosage of the drug substances is distributed on a plurality of subunit, namely consisting of thousands of spherical particles with diameter of 0.05-2.00mm. Thus the multiparticulate dosage forms are the pharmaceutical formulations in which the active substance API is present as a number of small independent subunits. For the delivery of the recommended total dose, these subunits are filled into a sachet or into a capsule and encapsulated or compressed into a tablet and then administered in to the patient. Multiparticulates comprises of discrete particles , so they are called multipleunit system. As they have small size , so they have many advantages over single-unit systems e.g., multiparticulates are less dependent on gastric emptyting, resulting in less inter and intra-subject variability in gastrointestinal transit time.

O autorze

Dr. Ashu Mittal received his B.Pharm degree from University of Rajasthan, M.Pharm from Government college of Pharmacy, Karad, MS. and Ph.D from Uttar Pradesh Technical University.He has supervised over 45 post graduate students. Dr Mittal has over forty publications to his credit in foreign/international journals of high scientific impact.