Nucleic Acids: Structures, Properties and Functions

ISBN-13: 9780935702491 / Angielski / Twarda / 2000 / 794 str.

Donald M. Crothers; Victor A. Bloomfield; Jr. Ignacio Tinoco

Opis

Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.

Spis treści

Introduction.- Bases, Nucleosides and Nucleotides.- Chemical and Enzymatic Methods.- Nucleic Acid Structures from Diffraction Methods.- Structure and Dynamics by NMR.- Electronic and Vibrational Spectroscopy.- Theoretical Methods.- Conformational Changes.- Size and Shape of Nucleic Acids in Solution.- Supercoiled DNA.- Interaction of Nucleic Acids with Water and Ions.- Interaction and Reaction with Drugs.- Protein-Nucleic Acid Interactions.- Higher Order Structure.- Index.

O autorze

VICTOR A. BLOOMFIELD, University of Minnesota
DONALD M. CROTHERS, Yale University
IGNACIO TINOCO, University of California, Berkeley