Non-Coding Rnas in the Vasculature

ISBN-13: 9783319529431 / Angielski / Twarda / 2017 / 101 str.

Thomas Thum; Stefanie Dimmeler

Opis

The main topics discussed include the role of regRNAs in vascular development and angiogenesis, ischemic cardiovascular disease and repair mechanisms, diabetic and metabolic vascular disease, atherosclerosis and vascular inflammation, as well as diagnostics of vascular disease using circulating miRNAs.

Spis treści

1. Non-coding RNAs in the vasculature.- Introduction (Thomas Thum, Stefanie Dimmeler).- Non-coding RNAs in vascular Development and Angiogenesis (Nathan Lawson or  Didier Steinier).- 2. Diagnostics of Vascular Diseases using circulating miRNAs.- 2.1 Basic and Technical Principles (Manuel Mayr).- 2.2 Diagnostics use of circulating miRNAs in cardiovascular diseases (Andreas Zeiher , Stephan Fichtlscherer).- 2.3 Non-coding RNAs in Ischemic cardiovascular disease and repair mechanisms (incl. AMI,  cell therapy) (Ulf Landmesser).- 3. Non-coding RNas in Diabetes and Metabolic Diseases.- 3.1 Non-coding RNAs in vascular complications of Diabetes (Costanza Emanueli).- 3.2 Non-coding RNAs in Metabolic Diseases, Cholesterol Metabolism (Carlos Fernandez-Hernando).- 3.3 Non-coding RNAs in Atherosclerosis and Vascular Inflammation (incl. aging processes and aneurysms, platelelets)(Christian Weber, Feinberg).- 4. Outlook and Perspectives (long non coding RNAs, microvesicles, new therapies, ect) (Thomas Thum, Stefanie Dimmeler).

O autorze

Prof. DDr. Thomas Thum, Institute of Molecular and Translational Therapeutic Strategies Hannover. Medical School Carl-Neuberg Str. 1.  30625 Hannover, Germany Email: Thum.Thomas@mh-hannover.de 

Prof. Dr. Stefanie Dimmeler, Institute for Cardiovascular Regeneration Centre of Molecular Medicine, Goethe University Frankfurt. 60590 Frankfurt, Germany Email: dimmeler@em.uni-frankfurt.de

Blurb

This book focuses on the importance of regulatory RNAs in the vasculature. The main topics discussed include the role of regRNAs in vascular development and angiogenesis, ischemic cardiovascular disease and repair mechanisms, diabetic and metabolic vascular disease, atherosclerosis and vascular inflammation, as well as diagnostics of vascular disease using circulating miRNAs. Lastly, it offers an overview of emerging topics such as microvesicle-mediated miRNA cellular trafficking and the vascular importance of long non-coding RNAs. It is an invaluable resource for academics, researchers and students working in the field of vascular biology.