Nitric Oxide and the Regulation of the Peripheral Circulation

ISBN-13: 9780817640460 / Angielski / Twarda / 1999 / 362 str.

Dennis B. McNamara; Philip J. Kadowitz; P. Kadowitz

Opis

Nitric oxide is involved in the regulation of the circulation in physiologic and pathophysiological conditions. Evidence indicates that alterations in endothelial production of nitric oxide may be involved in the pathogenesis of central hypertension, pulmonary hypertension, renal disease and coronary vasopastic disorders. In addition to being involved in regulation of the circulation in physiologic and pathophysiologic conditions, the inducible form of the enzyme may play a role in the refractory hypertension.

Spis treści

1. NO in the Regulation of Blood Flow: A Historical Overview; 2.
Regulation of Intracellular Ca2+ by Cyclic GMP-Dependent Protein
Kinase in Vascular Smooth Muscle Cells; 3. Oxidants and Vascular NO
Signaling; 4. Role of Na+-K+-ATPase in NO-Induced Relaxation; 5.
Purinergic Receptors, NO and Regional Blood Flow; 6. NO Derived from
Perivascular Nerve and Endothelium; 7. NO & Hypertension; 8. NO in
Control of the Cerebral Circulation; 9. Intravenous Anesthetics in the
Pulmonary Circulation; 10. Inhaled NO Therapy for Acute Respiratory
Failure; 11. Clinical Applications of Inhaled NO; 12. NO and the
Perinatal Pulmonary Circulation; 13. NO and the Pulmonary Circulation
in the Adult; 14. Role of NO in the Skeletal Muscle Vascular Bed; 15.
NO and Hepatic Circulation; 16. NO and the Gastrointestinal
Circulation; 17. Uterine Effects of NO; 18. NO Effect on Penile Blood
Flow and Lower Genitourinary Tract Function; 19. Role of NO in the
Regulation of Renal Blood Flow; 20. Role of NO in the Regulation of
Renal Function in Conscious Animals; 21. Modulation of Renal
Microvascular Responsiveness by NO.