New Trends in Haemostasis: Coagulation Proteins, Endothelium, and Tissue Factors

ISBN-13: 9783540532750 / Angielski / Miękka / 1990 / 270 str.

Job Harenberg; Dieter L. Heene; Gerd Stehle

Opis

Based on a symposium held in 1990 at the Heidelberg Academy for the Humanities and Sciences.

Spis treści

Endothelial Functions and Haemostasis.- Structure, Shape and Function of Glycosaminoglycans.- Structure and Metabolism of Glycosaminoglycans.- Fibrin Polymerization and Its Role in Regulating Haemostasis.- Function of von Willebrand Factor in Plasma.- Biosynthesis and Assembly of the Factor VIII — von Willebrand Factor Complex.- Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function and Induction of a Novel Procoagulant Activity.- Tissue Factors and Endothelium.- Platelet Adhesion; A Concerted Action of Hemodynamic and Biochemical Processes.- Modulation of Endothelial Functions by Advanced Glycosylation End Products.- Procogulant Activities of Leukocytes.- Cytokine Induced Stimulation of Endothelial Cells in Vitro.- Anti-Platelet Treatment of Metastasis.- The Molecular Anatomy of Vitronectin as Extracellular Regulator Protein: Multifunctional Properties of the Heparin-Binding Domain.- Mode of Action of Annexin V (Vascular Anticoagulant Alpha), A Protein Synthesized by the Vessel Wall.- Coagulation Inhibitors and Haemostasis.- Clinical Pharmacologal Profile of Low Molecular Weight Heparins.- Anticoagulant Actions of Sulphated Polysaccharides.- Development of Synthetic Proteinase Inhibitors as Anticoagulant Agents.- Antithrombin and Its Deficiency States.- “New” Coagulation Inhibitors.- Biological Function of Vitamin K Antagonists.- Plasminogen Activator Inhibitors: Biological Effects.- Fibrin-Specific Clot Lysis with Single Chain Urokinase-Type Plasminogen Activator (scu-PA).- Antibody — Mediated Thrombolysis: Promise and Problems.- Thromboembolism: Detection and Prophylaxis.- Causation and Prevention of Coronary Thrombosis: Present Situation.- Non-Invasiva Diagnostic Techniques in Deep Vein Thrombosis.- Evaluation of the Bleeding Effects of Antithrombotic Drugs.- List of Participants.- List of Sponsors.

O autorze

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