New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads

ISBN-13: 9780128146194 / Angielski / Miękka / 2018 / 710 str.

Mohd Sajjad Ahmad Khan; Iqbal Ahmad; Debprasad Chattopadhyay

Spis treści

Section 1: Introduction to Herbal Therapeutics 1. Herbal Medicine: Current trends and future prospects 2. Diversity of bio-active compounds and their therapeutic potential 3. Ethnomedicinal wisdom: An approach for antiviral drug development 4. Plant derived prebiotics and its health benefits

Section 2a: Biological activity and discovery of new compounds from herbs, medicinal plants and herbal medicine 5. Moroccan medicinal plants as anti-infective and antioxidant agents 6. Anti-inflammatory properties of herbs in oral infection 7.Bioactive molecules, pharmacology and future research trends of Ganoderma lucidium as a cancer chemotherapeutic agent 8. Indian berries and its active compounds: therapeutic potential  in cancer prevention 9. Prospects of essential oils in controlling  pathogenic biofilm 10. Anticancer phytocompounds: Experimental and clinical updates 11. Plant derived molecules in managing HIV infection

Section 2b: Mechanism of action plant derived products/medicine 12. Current Strategy to target bacterial quorum sensing and virulence by phytocompounds 13. Understanding biochemical and molecular mechanism of complications of glycation and its management by herbal medicine 14. Insights of Phyto-compounds as anti-pathogenic agents: Controlling strategies for inhibiting biofilms and quorum sensing in Candida albicans 15. Neem Leaf Glycoprotein in Cancer Immunomodulation and Immunotherapy 16. Role of phytomedicine in diabetes and cardiovascular diseases 17. Plant-derived Immuno-modulators

Section 3: Pharmacokinetics, interaction and toxicity profile of phytocompounds 18. Herb and modern drug interactions: Efficacy, quality and safety aspects

Section 4: New dimensions in phytotherapy research and applications 19. High Throughput Virtual Screening (HTVS) of natural compounds & exploration of their Bio-molecular mechanisms: An in silico approach 20. Plant extracts and phytocompounds in management of Malaria 21. Assessment of antimicrobial activity of different phytochemicals against enteric diseases in different animal models 22. Nanoparticles in Ayurvedic medicine: potential and prospects 23. Nanoparticles-based delivery of phytomedicines: Challenges and opportunities 24. Phytomedicine: A potential alternative medicine in controlling neurological disorders

O autorze

Dr. Khan obtained his Ph.D. in Agricultural Microbiology from Aligarh Muslim University, Aligarh, India. He has been the recipient of a Post Graduate Merit Scholarship and University Gold Medal in his M. Sc. Programme. He has experience of working in research projects and teaching at graduate and post graduate levels. Dr. Khan has been teaching microbiology, phytomedicine, molecular biology and immunology to these students. He has more than five years of research and academics experiences by serving as a Senior Research Fellow of Indian Council of Medical Research, New Delhi, India; Research Associate at Council of Scientific and Industrial Research, Institute of Microbial Technology, Chandigarh, India. He gained international experiences in research and teaching by serving as Post-Doctoral Fellow in Phytomedicine Programme with the prestigious group of Prof. J. N. Eloff in University of Pretoria, South Africa; and as an Assistant Professor in Biotechnology at Yenugnam University, South Korea. His research work had contributed significantly in the area of medicinal plants for pharmaceutical and applied industrial biotechnology and microbiology. He had published seventeen research papers and two review article in referred journals so far. He has contributed as author in seventeen book chapters. He has one book to his credit as first authorship and reviewer of more than 10 peer reviewed journals from publishers of Elsevier, Springer, Wiley, Taylor and Francis. His overall research activity has led him with a cumulative impact factor of papers published, 29; total number of citations, 633; and highest citation of a single paper being 156. His thrust area of current research work includes natural products for their novel anti-infective activity against drug-resistant pathogenic bacteria and fungi especially Candida albicans and Staphylococcus aureus focusing on anti-biofilm activity. Dr. Iqbal Ahmad obtained the M. Phil (1991) and the Ph. D. degree (1994) in Ag. Microbiology from Aligarh Muslim University and worked at Central Drug Research Institute, Lucknow (1989-1994) before joining as a lecturer at the Institute of Agriculture. Currently he is visiting Professor in the Department of Biology, UmmAl Qura University, Makkah, Saudia Arabia for a short visit since 28th May 2016. He has guided 10 Ph.D. and 52 M.Sc. dissertations, completed five Research Projects, edited 10 books and published more than 112 original research papers and 45 Book Chapters. Interdisciplinary Research work has also been conducted with experts in Applied Chemistry, Botany, Chemistry and Biotechnology. Dr. Ahmad is reviewer of various international and national scientific journals published by reputed International Publishers such as Nature Group, Elsevier, Springer, Wiley, Taylor and Francis etc. Major area of his teaching interests includes: General microbiology, Pathogenic microbes and drug resistance, soil microbiology, industrial microbiology and fermentation technology, Biomolecules, bacterial genetics and plasmid biology. Dr. Debprasad Chattopadhyay (PhD) has over 38 years of research experience in the field of Microbiology, Virology, Traditional Medicine, Ethnomedicine, and Molecular Medicine in identifying nature-based leads against difficult-to-treat diseases through documentation and validation of purity, safety, and potency (PSP) of traditional practices of Indian tribes with mode or molecular mechanism of action. He is currently the editor of the prestigious journal Frontiers in Pharmacology, editorial board member of the Journal of Ethnopharmacology, and reviewer of more than 40 peer-reviewed journals. He is the recipient of several awards such as Outstanding Ethnopharmacologist (2016), Best Science Communicator (2009), Amiya Bose Oration (2008), R.V. Rajam Endowment of IMA 1998, and International Society of Chemotherapy Young Scientist 1991.