New Horizons for Failing Heart Syndrome

ISBN-13: 9784431669470 / Angielski / Miękka / 2012 / 237 str.

Shigetake Sasayama

Opis

New Horizons for Failing Heart Syndrome brings together the latest knowledge on heart failure syndrome and the status of research on heart failure in Japan, compiling the results of the Japanese Circulation Society's second research series. Contents include the molecular mechanism of heart failure, mechanics of contraction of the failing heart, energetics of the failing heart, exercise physiology, and new aspects of management of heart failure. The Japanese Circulation Society's 3-year project for research on heart failure was conducted in two series, the first from 1988 to 1991 and the second from 1992 to the spring of 1995. The present volume embodies the most up-to-date overview of current research being carried out in Japan today, and will be of special interest to cardiologists, researchers, and other practitioners in the field.

Spis treści

1 Molecular Mechanism of Heart Failure.- Molecular Aspects of Mechanical Stress-Induced Cardiac Hypertrophy and Failure.- Calcium-Activated Neutral Proteases and Myocardial Protein Catabolism.- Cytoskeletal Changes in the Calcium-Overloaded Heart.- 2 Mechanics of Contraction of the Failing Heart.- Cardiac Utilization of the Momentum of Blood.- Two Major Pumps of the Heart: Difference and Interdependence of the Right and Left Ventricles.- Dahl Salt-Sensitive Rats: Model to Study Transitions from Compensatory Hypertrophy to Left Ventricular Failure.- Precordial or Epicardial Input of Phase-Controlled Minute Vibration: Effect on Coronary Flow Rate in Regional Ischemia.- 3 Energetics and Exercise.- Mechanoenergetics of Acute Failing Hearts Characterized by Oxygen Costs of Mechanical Energy and Contractility.- Left Ventricular Contractile and Energetic Dysfunction After Recovery from Acidosis.- Diagnostic Value of the Transient Response of Oxygen Consumption to Exercise in Cardiac Patients: Ramdom Noise Approach.- 4 Medical Treatment of Heart Failure.- Mechanisms of Novel Cardiotonic Agents Developed to Treat the Failing Heart Syndrome.- Positive Inotropic Therapy for Chronic Heart Failure: New Perspective on Therapeutic Strategies.- Cytokines and Heart Failure: Immunomodulating Agents for the Management of Heart Failure.