New Discoveries in the Behavioral Neuroscience of Attention-Deficit Hyperactivity Disorder

ISBN-13: 9783031118012 / Angielski / Twarda / 2022

Opis

New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research.  The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.

Spis treści

CLINICAL PROFILE AND TREATMENTS.- ADHD in children and adults:  diagnosis and prognosis.- Treatment strategies.- Psychostimulants – treatment efficacy and problems.- Recent developments and future options for pharmacological treatments for ADHD.- GENETICS.- Genetics of ADHD (including CNVs).- Genes , cognitive function and ADHD.- Epigenetics and ADHD.- CO-MORBIDITY.- ADHD and comorbid depression.- ADHD and autism.- Aggression and ADHD.- Obesity and ADHD (+ cytokines?).- Sleep circadian rhythms and ADHD.- Substance misuse .- ASSESSING BRAIN FUNCTION / DYSFUNCTION.- EEG and ADHD (the skeptical view).- Update on imaging – with connectivity.- Visual processing substrates for ADHD.- Cortical microstructure / connectivity.- ANIMAL AND IN VITRO STUDIES.- Critique of animal models.- Update on circuits for impulsive behaviour.- Zebrafish.- Update on DA transporter and ADHD.- Arousal, noradrenaline and ADHD.- FUTURE DIRECTIONS.- Stem cells for disease modelling.- Microbiome and ADHD.- Adult ADHD.