New Aspects of Storage and Release Mechanisms of Catecholamines

ISBN-13: 9783642494659 / Angielski / Miękka / 1970 / 301 str.

Hans-Joachim Schumann; Gunther Kornenberg

Spis treści

Welcome.- Opening Remarks.- Session 1 Origin and Axonal Transport of Adrenergic Nerve Granules.- Studies on the Origin of the Granulated and Non-granulated Vesicles.- Discussion.- The Effects of Drugs on Axonal Transport of Amine Storage Granules.- Discussion.- Invited Comment.- Discussion.- Session 2a Mechanism of Transmitter Release with Special Reference to the Problem of Exocytosis (I).- Opening Remarks.- Immunological Properties of Chromogranin.- Discussion.- Immunohistochemical Localization of Chromogranins in Sheep Sympathetic Neurons and their Release by Nerve Impulses.- Discussion.- Session 2b Mechanism of Transmitter Release with Special Reference to the Problem of Exocytosis (II).- Quantal Aspects of the Secretion of Catecholaminess and Dopamine-?-hydroxylase from the Adrenal Medulla.- Discussion.- Some Aspects of the Quantal Release of the Adrenergic Transmitter.- Discussion.- Some Further Aspects on the Release of the Adrenergic Transmitter.- Discussion.- Quantal or Graded Secretion of Adrenal Medullary Hormone and Sympathetic Neurotransmitter.- Discussion.- Session 3 Chemical Sympathectomy.- Chemical Sympathectomy with 6-Hydroxydopamine.- Session 4a Effects of Drugs on Uptake and Release of Catecholaminess (I).- Effect of Some Metabolic Factors and Drugs on Uptake and Release of Catecholaminess in vitro and in vivo.- Discussion.- Saturation of the Uptake of Noradrenaline as a Determinant of Pharmacological Effects.- Discussion.- Cholinomimetic Drugs and Release of the Adrenergic Transmitter.- Discussion.- Session 4b Effects of Drugs on Uptake and Release of Catecholaminess (II).- Membrane Effects of Catecholamines Releasing Drugs.- Discussion.- Effect of Angiotensin on Noradrenaline Release of the Isolated Rabbit Heart.- Discussion.- Neuronal and Hormonal Control of Tyrosine Hydroxylase and Phenylethanolamine N-methyltransferase Activity.- Discussion.- Session 4c Effects of Drugs on Uptake and Release of Catecholaminess (III).- Effect of Drugs on Amine Uptake Mechanisms in the Brain.- Discussion.- Release of Monoamines in the Central Nervous System.- Discussion.- The Effect of Different Neuroleptic Drugs on the Monoamine Neurons of the Rat Brain.- Discussion.- Release of Catecholaminess from the Hypothalamus by Drugs and Electrical Stimulation.- Discussion.- Session 5 General Discussion.- Author Index.