Neuroviral Infections: General Principles and DNA Viruses

ISBN-13: 9781466567191 / Angielski / Twarda / 2013 / 396 str.

Sunit K. Singh;Daniel Ruzek

Opis

Viral infections of the central nervous system or neurotropic viruses are often lethal. Understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book provides in-depth information about each individual virus, the diseases they cause, and the mechanisms of spread of those diseases. Addressing both clinical and basic science aspects, the text covers such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host pathogen immune interaction as well as disease detection, treatment, and prevention.

Spis treści

Principles of Viral Infections of the Nervous System: Neuroviral Infections: A Historical Perspective. Neuroviral Infections and Immunity. Controlling Neuroinflammation: Lessons from Rabies Virus. Laboratory Diagnosis of CNS Viral Infections. New Trends in Antiviral Therapy of CNS Infections. Animal Models of Viral Encephalitis. Neurotropic DNA Viruses and their Diseases: Herpes Simplex Virus and Human CNS Infections. CNS, Neurological Infections Caused by the Herpesvirus Varicella-Zoster Virus (VZV), and Models of VZV Neurotropism. Epstein–Barr Virus and CNS Infections. Cytomegalovirus (CMV) Infection. Human Herpesvirus 6A, 6B, and 7 Encephalitis. The Human Polyomavirus JC and Progressive Multifocal Leukoencephalopathy.