Neurotoxicity of tri ortho cresyl phosphate (TOCP) in adult hen : Light and Electron microscopic study

ISBN-13: 9783659908637 / Angielski / Miękka / 2016 / 104 str.

Bahaa Al-Sereah; Saleh Majeed; Zainab Khudeir

Opis

The study was done as neurotoxicity research project on adult hen.Tri ortho cresyl phosphate (TOCP) was chosen as the best example for organophosphorus poison or neurotoxicity as most of the neurotoxicity research work was done by using (TOCP). In the present topic there will be various description of light microscopic changes but mainly will be using electron microscope as it is the only way to describe in detail any changes in peripheral and central nervous system including the main organelle e.g. mitochondria and synopsis.The important of this work as it will be the best positive control for any insecticide or other chemical compound which can be develop by pharmaceutical company for use by man and animals. The birds(leghorn) which used were adult hen of (5-6 month) of age.The study was done in two forms, first form as acute delayed neurotoxicity by using single dose of 500 mg/kg for 21 days after that bird were sacrificed and light and electron microscopic was done on central and peripheral nervous system. The other part was sub chronic of 90 days by using 5 mg/kg as high dose, 2.5 mg/kg as intermediate dose and 1.25 mg/kg as low dose.

O autorze

Assistant professor Bahaa Abdulhussein Al-sereah graduated from Veterinary Medicine College 2004 (BVMSc).2005-2007 Working as Postgraduate Student doing MSc in Poultry Diseases.2015-2016 I work as Postgraduate Student doing PhD in Poultry Nutrition.I have 34 research, also a book published in German about toxic effect of contraceptive in women's.