ISBN-13: 9781493979325 / Angielski / Miękka / 2018 / 306 str.
ISBN-13: 9781493979325 / Angielski / Miękka / 2018 / 306 str.
Cognitive and behavioral phenotypes are full of potential as aids to the accurate diagnosis of cognitive disorders. This review, pioneering in its depth and focus, maps an organizing structure for cognitive phenotypes before analyzing notable varieties.
This expansive text applies the latest knowledge of neural and cognitive biomarkers to the contemporary bioinformatics and “omics” landscape, and to neuropsychology and psychiatric research and practice. Focusing on neurophenotypes and endophenotypes, it updates concepts of neurocognitive and behavioral functioning, normal and disordered processes and structures, and their myriad relationships within the larger context of the nervous system. Specialized chapters delve into neural and cognitive gray areas that may be classified as neurophenotypes or cognitive endophenotypes, including face perception, reward deprivation, EEG data, and fear conditioning. These advances signal a new accuracy in neuroscience, from a more precise fit between data, tools, and models to more effective diagnosis, treatment, and policy.
Among the topics covered:
Neurophenotypes and endophenotypes are critical discoveries in a developing field, and the analysis in Phenotypes spotlights their utility to neuropsychologists, neurologists, psychiatrists, and cognitive neuroscientists. This clarion work prepares research and clinical professionals for the world of technology- and science-based paradigms to come.
Susan Santangelo, Sc.D. is associate professor at the Harvard Medical School (Psychiatry) and the Harvard School of Pulbic Health (Epidemiology), where she has been a faculty member since 1994. She is Director of Statistical Genetics and Genetic Epidemiology in the Psychiatric and Neurodevelopmental Gentics Unit within the Center for Human Genetic Research at Massachusetts General Hospital. Her work is focused on the gene finding and phenotype delineation for a number of psychiatric disorders, particularly autism and schizophrena. As a nationally and internationally recognized expoert on the genetics of autism, Dr. Santangelo has served as an ad hoc member of the Scienctific Advisory Board for the National Alliance for Autism Research (NAAR) since 1999 and continues in that role for Autism Speaks since its merger with NAAR. She serves on the steering committee of the Autism Consortium and on the editorial boards of Molecular Autism (BMC) and the American Journal of Medical Genetics Part B Neuropsychiatric Genetics. She was the recipient of a Career Development Award from the NIMH. Vinoth Jagaroo, Ph.D. is associate professor in the Department of Communication Sciences and Disorders at Emerson College and in the Department of Psychiatry and the Behavioral Neuroscience Program at Boston University School of Medicine. Dr. Jagaroo is a member of the Cognitive Neuroscience Society, the International Neuropsychological Society, the Society for Neuroscience, and the American Neuropsychiatric Association. He is the founding member of the Society for Neuroinformatics in Neuropsychology.
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