Neuroinflammation in Vascular Dementia

ISBN-13: 9780128234556 / Angielski / Miękka / 2022

Gary Rosenberg

Spis treści

1. Clinical Aspects of Diagnosis
2. Neuroimaging Methods
3. Role of CSF and Blood in Diagnosis
4. Classification of Subtypes of Vascular Dementia
5. Neuroinflammation
6. Animal Models Relevant to Vascular Disease
7. Molecular Pathways
8. Mechanisms of White Matter Injury
9. Machine Learning and Precision Medicine
10. Future Directions

O autorze

Gary Rosenberg, MD is a Professor of Neurology with joint appointments in Departments of Neuroscience, Cell Biology and Physiology, and Mathematics and Statistics at the University of New Mexico. He was Chairman of Neurology
before becoming director of the UNM Center for Memory and Aging. He is a leading authority in dementia secondary to vascular disease. He discovered the role of the matrix metalloproteinases in the brain and was the first to describe the
important role they played in disruption of the blood-brain barrier. He is an expert in neuroimaging and was one of the first investigators to use dynamic contrast-enhanced MRI to measure blood-brain barrier permeability in humans. He is currently principal investigator of one of centers in the NIH MarkVCID consortium for the study of biomarkers in vascular cognitive
impairment and the impact of vascular disease on Alzheimer's disease. He has published over 160 peer-reviewed papers and two books on brain fluids and metabolism.