Neurochemical Mechanisms in Disease

ISBN-13: 9781493940851 / Angielski / Miękka / 2016 / 844 str.

John P. Blass

Opis

This latest volume of Advances in Neurobiology deals with the Neurochemistry of disease. Written by experts in the field, its chapters cover both human diseases and animal "model" diseases, through research on human and animal tissues.

Spis treści

Chapter 1: Mechanisms versus Diagnoses John Blass Chapter 2: Molecular Mechanisms of Neuronal Death Carol Troy Chapter 3: Animal Models of Neurodegenerative Diseases Mohamed Jaber Chapter 4: Vitamins and Vitamin Deficiencies Roger Butterworth Chapter 5: Brain Edema in Neurological Disease G.A. Rosenberg, Eduardo Candelario-Jalil & Saeid Taheri Chapter 6: Pathology of Monoamine Transporters Eric Barker Chapter 7: Glutamate and Glutamine in Brain Disorders Arne Schousboe Chapter 8: The X-linked Mental Retardation Linda Van Aelst Chapter 9: Cognitive Deficits in Neurodegenerative Disorders Ivan Bodis-Wollner & Herman Moreno Chapter 10: NFkappaB in Brain Diseases C.-X. Gong Chapter 11: Trinucleotide-Expansion Diseases Arthur JL Cooper Chapter 12: Neuroinflammation David Lawrence Chapter 13: Neurochemistry of Autism S.H. Fatemi & T. Folsom Chapter 14: RNA Pathologies in Neurological Disorders Kinji Ohno & Akio Masuda Chapter 15: Pain Gyongyi Horvath Chapter 16: Biology of Demyelinating Diseases Danielle Pham-Dihn & Nicole Baumann Chapter 17: Brain Protein Oxidation and Modification for Good or Bad in Alzheimer’s Disease D.A. Butterfield Chapter 18: Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities Mark- Smith Chapter 19: Tau and Tauopathies Robert Mathew and PS Mathuranath Chapter 20: Zinc, Zinc Transport and Sequestration Proteins in the Brain in the Progression of Alzheimer’s Disease Mark A. Lovell Chapter 21: The Genetics of Alzheimer’s Disease and Parkinson’s Disease Lynn M. Bekris, Chang-En Yu, Thomas D. Bird & Debby Tsuang Chapter 22: Nicotine Receptors in Brain Diseases J.A. Stitzel Chapter 23: Lysosomal Storage Disorders Gregory M. Pastores Chapter 24: Genetic signaling in glioblastoma multiforme: a current overview W.J. Lukiw & F. Culicchia

O autorze

John P Blass, MD, PhD, has been studying the chemistry of diseases of the brain for over half a century: as an undergraduate at Harvard, as a graduate student with Henry McIlwain, as a postdoctoral fellow first with Heinrich Waelsch and then with Daniel Steinberg, during eight years at the Mental Retardation Center at UCLA, and since 1978 as Burke Professor of Neurology, Neuroscience, and Medicine at Weill Cornell Medical College in New York City (now professor emeritus). His work has concentrated on the role of reductions in brain metabolism in Alzheimer’s disease and other disorders impairing cognition.

Blurb

This volume of Advances in Neurobiology deals with the Neurochemistry of disease, with chapters covering both human diseases and animal “model” disorders. Specific diseases are covered in chapters on neurodegenerations such as Alzheimer’s and Parkinson's, on demyelinating diseases, on autism, and so on. This volume on Neurochemical Mechanisms in Disease strives to encourage more chemically based definitions of these and other diseases.