Nephrotoxicity in the Experimental and Clinical Situation: Part 1

ISBN-13: 9789401080125 / Angielski / Miękka / 2011 / 488 str.

P. H. Bach; E. a. Lock

Spis treści

1. Fixation of renal tissue for cytochemical evaluation.- 2. The application of histochemistry at the light microscopic level to the study of nephrotoxicity.- 3. Cryomicrotomy of renal tissue, and the use of X-ray microanalysis and autoradiography at the light and electron microscopic levels.- 4. Fixation of kidney tissue for morphometric study.- 5. Correlating structural and functional changes in nephrotoxic renal injury.- 6. Naturally occurring renal disease in non-human primates.- 7. Chemically induced epithelial tumours and carcinogenesis of the renal parenchyma.- 8. Assessment of the kidney in relation to blood pressure regulation.- 9. Renal slices and perfusion.- 10. The use of single nephron techniques in renal toxicity studies.- 11. Prostaglandins and other eicosanoids.- 12. Xenobiotic metabolism in the mammalian kidney.- 13. Metabolism of glutathione in the kidney.- 14. Metabolic activation of halogenated chemicals and its relevance to nephrotoxicity.