Natural Products for Cancer Chemoprevention: Single Compounds and Combinations

ISBN-13: 9783030398576 / Angielski / Miękka / 2021 / 629 str.

John M. Pezzuto; Ole Vang

Spis treści

Chapter 1. Chemoprevention of Cancer - Past,Present, and Future.- Chapter 2. Resveratrol for Cancer Prevention: Current Gaps and Opportunities.- Chapter 3. Pterostilbene as a Potent Chemopreventive Agent in Cancer.- Chapter 4. Pharmacokinetics and Bioavailability Enhancement of Natural Products.- Chapter 5. Vitamin D Compounds and Cancer Stem Cells in Cancer Prevention.- Chapter 6. Anti-cancer Effects of Silibinin – The Current Status in Cancer Chemoprevention.- Chapter 7. Adjuvant Value of Turmeric Extract (Containing Curcumin) in Colorectal Cancer Management.- Chapter 8. Cancer Prevention by Tea Polyphenols.- Chapter 9. The Chemopreventive Power of Isothiocyanates.- Chapter 10. Xanthohumol and Structurally Related Prenylflavonoids for Cancer Chemoprevention and Control.- Chapter 11. Anthocyanins and Cancer Prevention.- Chapter 12. Grape ChemopreventiveAgents AgainstAngiogenesis and Metastasis.- Chapter 13. Punicagranatum L. Constituents for Cancer Prevention, Chemosensitisation and Therapeutic Treatment.- Chapter 14. Cancer ChemopreventivePotential of Epidermal Growth Factor Receptor Inhibitors from Natural Products.- Chapter 15. Anti-cancer Dynamics of Natural Phytochemical Inhibitors of Cyclin-dependent Kinases.- Chapter 16. Pro-apoptotic Properties of Chemopreventive Agents.- Chapter 17. The Use of Anti-inflammatory Agents for Cancer Chemoprevention.- Chapter 18. Combination Chemoprevention by Targeting the Epigenome.- Chapter 19. Perspective – a positive cocktail effect of the bioactive components in the diet.

O autorze

John M. Pezzuto is Professor, Dean and Vice President at Long Island University in Brooklyn, New York. With long standing interest in cancer chemoprevention, he is an author or co-author of over 600 papers published in the scientific literature, including a seminal paper that appeared in Science describing the cancer chemopreventive potential of resveratrol. He is the editor of several books, included Grapes and Health and Topics in Current Chemistry. Vol. 329. Natural Products in Cancer Prevention and Therapy, both published by Springer.

Ole Vang is associate professor at Roskilde University, Roskilde. He has studied the health effects of bioactive compounds for his entire career, with emphasis on the effects mediated by indoles and resveratrol. He organized biannual international resveratrol conferences (2010-2018) together with several regional resveratrol meetings during the same period of time. His current research focus is on the combinatory effect of mixtures of bioactive components. He is an author or co-author of over 50 papers published in the scientific literature.

 

Blurb

This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models.

Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.