Natural Product Experiments in Drug Discovery

ISBN-13: 9781071626825 / Angielski / Twarda / 2022

Opis

This detailed volume explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. 

Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.

Spis treści

1. Phytochemical, Antioxidant, and Flavonoid Investigation of Methanolic Leaf Extract of Piliostigma Thoningii (Schum.)

            Michael O. Afolayan, Rebecca O. Omosimua, Adewale E. Fadeyi, Onyinye C. Aguzue, Olayinka T. Asekun, and Oluwole B. Familoni

 

2. A Comparative Evaluation of Organoleptic, Physicochemical, Proximate, and Mineral Composition of Syzygium laetum and Syzygium occidentale, Endemic to Western Ghats: A Search for Low-Cost Nutraceuticals

            Snehalatha V.R. and Rasmi A.R.

 

3. Chemical Characterization, Biological Activities, and Some Medicinal Uses of Different Sweet Basil (Ocimum basilicum L.) Genotypes

            Gulsum Yaldiz, Mahmut Camlica, Yashashree Pradhan, and Ahmad Ali

 

4. Estimation of Primary, Secondary Metabolites, and In Vitro Free Radical Scavenging Activities with Ficus tsjahela Burm. F. Crude Extracts

            Thamaraikani Velmurugan, Amala Divya Sebasthi, and Sekar Thangavel

 

5. Evaluating the Lipid Profile and Mineral Composition of the Seed Oil of Caesalpinia sappan L. (Caesalpiniaceae)

            Nagaraju S., Thippeswamy T., and Ravi Kumar H.

 

6. Phytochemical Screening, Physicochemical Analysis, and Powder Characterization of Selected Litsea Species Endemic to the Southern Western Ghats

            Ummu Habeeba K. and Rasmi A.R.

 

7. Metabolite Profiling of Bioactive Compounds in Selected Species of Gomphostemma Wall. ex Benth. from the Western Ghats by GC-MS Analysis

            Sajitha Menon K. and John E. Thoppil

 

8. Phytochemistry and Pharmacology of Aromatic Medicinal Plant Commiphora caudata(Wight &Arn.)Engl.

            Ch. Srinivasa Reddy, K. Sri Rama Murthy, and K. Ammani

 

9. Unravelling the Phytochemistry of Ethnomedicinal Tree Pajanelia longifolia (Wild.) K. Schum.

            Smitha C.K., Udayan P.S., and Vaishnavi M.

 

10. Comparative Phycochemical Investigation and Antioxidant Content of Two Marine Seaweeds

            Amala Divya S., Thamaraikani V., Karthikeyan S., and Sekar T.

 

11. Evaluation of Nutritional, Antioxidant and Anti-Arthritic Activity of Hedychium coronarium J. Koenig Rhizome

            Benedict Mathews Paul, Gowtham Kannan, Sruthi S, Ashwini Lydia Manoharan, Gayathri Nataraj, and Parimelazhagan Thangaraj

 

12. Phytochemical, Pharmacognostic, and In Vitro Acetylcholinesterase Inhibitory Activities of Cipadesa baccifera Leaves

            Mary Sheeja and V. Gomathi

 

13. Comparative Study of Drug Efficiency of Scemecarpus anacardium and Tridax procumbens against Zika Virus

            Akshata Sharma, A. Aishwarya, S. Riyaz Sharif, Abhishek Biswal, Ivo Romauld S., and Vivek Pazhamalai

 

14. Evaluation of In Vitro Antioxidant Activity of Oldenlandia dineshii: An Endemic Plant from the Hillocks of Palakkad District, Kerala, India

            Prasanth M.K., Chandini C., and Leeja L.

 

15. Identification of Secondary Metabolites through HR-GC-MS: Antibacterial and Antifungal Activity from Root Fractions of Alstonia scholaris (L.) RBr. from Andhra Pradesh, South India

            Devarakonda Ramadevi, Radha Rayi, and Ganga Rao Battu

 

16. In Vitro Models on Inhibition of Inflammatory Mediators by Ethanolic Extract of Careya arborea Roxb. Bark in Lipopolysaccharide-Induced RAW 264.7 Cell Lines

            Bindu A.R. and N.A. Aleykutty

 

17. Pharmacological Elucidation of Antioxidant, Hypoglycemic, and Anti-Inflammatory Potentials of Phyllanthus candolleanus (Wights ARN) Chakrab.

            Mohammed Asiq, Gayathri Jagadeesan, Francis Jegan Raj Stephen, Anish Ruban S., Kasipandi Muniyandi, and Parimelazhagan Thangaraj

 

18. α-Glucosidase Inhibition and Upregulation of PPARγ by Flavonoid Naringenin from Tinospora sinensis Stem, a Possible Mechanism of Antidiabetic Activity

            Bobby S. Prasad and K.K. Srinivasan

 

19. Purification and Characterization of a Cysteine Protease from Sprouted Lablab purpureus Seed Radicle Extract: Its Effect on Blood Coagulation

            Thoyajakshi R.S., Nagaraju S., Ravikumar H., and Poornima D.

 

20. Effect of Sterilization Agents, Growth Regulators, and Activated Charcoal on Callus Cultures of Evolvulus alsinoides (Linn.) Linn

            Pavithra Sivaraja and Kannan Kilavan Packiam

 

21. Bryophytes: A Myriad Hue of Bio-Resources with Therapeutic Potentialities

            Manoj G.S., Greeshma G.M., Remya Krishnan, and Murugan K.

 

22. Recent Biotechnological Approaches for the Enhancement of Artemisinin Production from Cell Culture System of Artemisia annua L: Medicinal Plant with Potent Anti-Malarial Properties

            Ganesan Mahendran and Laiq ur Rahman

 

23. The Utility of Natural Mucilage from the Medicinal Plant, ‘Patha’ (Cyclea peltata), as an Alternative for Solidifying Agent in Cell Growth Media

            Anjana Krishnan, Jomy Joseph, and Sudha Kalyanikutty

 

24. Microwave Irradiation-Assisted Extraction and Synthesis of Silver Nanoparticles Using Tree Tomato Fruit Pulp (Solanum betaceum Sendt.) and Determination of In Vitro Cytotoxic Effect on MCF-7 Cells

            Mary Joseph, Aarthi Jeganathan, and Geetha Natesan

 

25. Characterization of Crystals Isolated from the Caesalpinia sappan Seeds: A Comparative In Silico Analysis on Bioactivity of Sappan Diterpenoids

            H. Ravi Kumar, S. Nagaraju, Kiran Krishnamurthy, N.S. Surendra, Srinivasarao Raghothama, T. Thippeswamy, T.P.N. Hariprasad, and Anjali Ganjiwalea

 

26. Computational Analysis of Natural Compounds as Potential Isocitrate Dehydrogenase 1 Inhibitor for the Treatment of Ovarian Cancer

            Nirmala Ganesan and Akshata Sharma

 

27. Drug Efficiency of Oroxylum Indicum and Taxus Wallichiana Against Colon-Associated Diseases: In Silico Studies

            Akshata Sharma, Varsha Karikalan, Bhuvaneswari Saikumar, and Sakthiselvan Punniavan

 

28. Gas Chromatography-Mass Spectrometry Analysis of Phytoconstituents from Garcinia gummi-gutta Seed Extract: Trypsin Inhibition Study of Extract and Molecular Docking Study

            Sumachirayu C.K., Kusuma C.G., Megha G.T., Vinod Gubbiveeranna, Bhavana S., Ravikumar H., and Nagaraju S.

 

29. In Silico Analysis of Anti-Inflammatory Activity of Quercetin from M. Calabura Fruit

            K. Preethi

 

30. Phytochemical Investigation, Molecular Docking Studies, and Biological Efficacy of Rhizome Essential Oil Composition of Costus Speciosus

            Mity Thambi and Tom Cherian

 

31. Ficus talboti King: Anti-Nociceptive and Anti-Inflammatory Properties of Methanol Extract of Stem Bark

            Karuppusamy Arunachalam, Sreeja Puthanpura Sasidharan, Thangaraj Parimelazhagan, and Xuefei Yang

 

32. Phytochemical and Antioxidant Analysis of Phellinus adamantinus and P. hohnelli

            Rajeswari S., Manian S., and Saikumar S.