Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases

ISBN-13: 9789811976551 / Angielski / Twarda / 2023 / 482 str.

Harish Dureja; Jon Adams; Raimar L?benberg

Opis

This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders. The initial chapter provides a brief introduction to lung diseases with a focus on the current landscape of natural polymers and trends in understanding the disease pathology. Several chapters of the book devoted to the latest technologies and advances in drug delivery systems include practical solutions on designing more effective drug delivery systems based on natural polymers that can be used in the management of lung diseases. Further, the book presents biodegradable and bio-reducible- natural polymers- based drug delivery systems for lung diseases. Towards the end, the book examines future prospects and challenges of natural polymers-based drug delivery systems in combating lung diseases. This book is useful for phytochemists, formulation/drug delivery, biological and translational researchers and clinicians working in the field of lung disorders.

Spis treści

Chapter 1_Introduction to Lung diseases. -Chapter 2_Natural polymers for drug delivery. -Chapter 3_Drug delivery based on various natural polymers for lung diseases. -Chapter 4_Plant-derived natural polymers employed in respiratory diseases. -Chapter 4.1_Cellulose-based drug delivery systems. -Chapter 4.2_Pectin derived drug delivery systems. -Chapter 4.3_Starch-based drug delivery systems. - Chapter 4.4_Cyclodextrin derived drug delivery systems. - Chapter 4.5_Gum-based drug delivery systems. - Chapter 4.6_Glucomannan and xyloglucan derived drug delivery systems. - Chapter 4.7_Arabinogalactan, latex based drug delivery systems. - Chapter 5_Animal-derived natural polymers employed in respiratory diseases. - Chapter 5.1_Chitosan-based drug delivery systems for respiratory diseases. - Chapter 5.2_ Albumin for application in DDS for lung diseases. - Chapter 5.3_Gelatin in DDS for treatment of lung disorders. - Chapter 5.4_Hyalouronan and chondroitin sulphate-based drug delivery systems. - Chapter 5.5_Insulin-based drug delivery systems. - Chapter 6_Microorganisms derived natural polymers employed in respiratory diseases. - Chapter 6.1_Xanthan gum-based drug delivery systems for respiratory diseases. - Chapter 6.2_Dextran for application in DDS for lung diseases. - Chapter 6.3_Pullulan in DDS for treatment of lung disorders. - Chapter 7_Algae derived natural polymers employed in respiratory diseases. - Chapter 7.1_Alginate based drug delivery systems for respiratory disease. -Chapter 7.2_Carrageenan based drug delivery systems for respiratory disease. -Chapter 7.3_Agar based drug delivery systems for respiratory disease. -Chapter 8_Clinical trails and Regulatory issues of natural polymers employed in respiratory diseases. -Chapter 9_Challenges of natural polymers-based drug delivery systems in combating lung diseases. -Chapter 10_Future prospects of natural polymers-based drug delivery systems in combating lung diseases.

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O autorze

Dr. Harish Dureja is Professor and Head, Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak. Dr. Dureja is also the Director, Centre for IPR Studies and Director, Professional Consultancy Cell. Dr. Dureja has more than 22 years of teaching experience. He also holds 18 years’ research experience in the field of nanoparticulate drug delivery, regulatory affairs and in silico ADME modeling. Dr. Dureja has been awarded with Gold-Medal for the best Ph.D. thesis and research projects worth 1.2 Crore from various funding agencies. He has filed an Indian patent and authored three books and more than twenty-five book chapters. He has published more than 200 research articles in various international and national journals of repute.  He worked as Chairman- Scientific Services Committee (LOC) during 69th IPC at Chitkara University, Rajpura. He also worked as content writer for e-Pathashala program of Ministry of Human Resources Development for Post Graduate course of Pharmaceutical Sciences for the paper novel drug delivery system. He has delivered more than 180 invited Lectures in various conferences, seminars and symposiums and has guided 60 PG scholars and 11 students for doctoral work. He has been awarded the MDU Best Researcher Award – 2020, Gold-Medal for Best Ph.D. Thesis, Best Paper Award - Prof. M.L. Khorana Memorial Prize Award – 2005 and Dr. R.L. Nicore award - 2018. He has published six special issues as a Guest Editor for the Journals published by Bentham Science Publishers, and one issue published by Frontiers, Switzerland. He is currently also serving as President, Association of Pharmaceutical Teachers of India (APTI) Haryana State Branch.

Prof Jon Adams is Distinguished Professor of Public Health, Founder and Director of the Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), and Deputy Head of School (Research), School of Public Health, University of Technology Sydney. Prof Adams has attracted over $20M in external grant funding and his work has involved interdisciplinary collaborations across many clinical, practice and project design areas. Jon has authored over 580 peer-reviewed academic publications and is Chief Editor of 8 international research books and author of over 70 book chapters. Jon is the only Australian researcher ever to have attracted 3 consecutive Government Fellowships (NHMRC and ARC) focused upon complementary and integrative health care and he was recently awarded a prestigious Fulbright Senior Scholarship (2019) to examine complementary and integrative medicine for vulnerable communities in Boston, US. Jon holds leadership roles at both the Public Health Association of Australia (PHAA) and the American Public Health Association (APHA) and his research has been commissioned by and/or partnered with the World Health Organization (WHO) and various Ministries of Health.

Prof Raimar Löbenberg holds a BS in pharmacy from the Johannes Gutenberg-University in Mainz, Germany. He received his PhD in Pharmaceutics from the Johann Wolfgang Goethe-University in Frankfurt in 1996 for his work in drug delivery using nanoparticles. He joined the University of Alberta in the year 2000. His research interests are in Biopharmaceutics to predict the oral performance of drugs and botanicals and inhalable nanoparticles to treat lung diseases like lung cancer, tuberculosis or leishmaniasis. He is founder and director of the Drug Development and Innovation Centre at the University of Alberta. He was president of the Canadian Society for Pharmaceutical Sciences 2014-2015. He is the member of the United States Pharmacopeia Dietary Supplement Expert Committee.  He is vice chair of the Specialty Committee of Traditional Chinese Medicine in Pharmaceutics of the World Foundation of Chinese Medicine Science. He is member of the Health Canada Scientific Advisory Committee on Pharmaceutical Sciences and Clinical Pharmacology. Dr Lobenberg is also the member of the Health Canada Scientific Advisory Committee on Opiate Abuse.

Dr. Andreoli Pinto´s educational background is in Pharmaceutical Sciences (Bachelor, Master’s and Ph.D.). Her career is more than 40 years of sound experience in Academia, being currently Full Professor in one of the most prestigious Universities in Brazil: University of São Paulo. Dr. Andreoli Pinto develops and run researches on Dosage Forms, focusing on Parenterals (formulation, analytical, microbiological and performance methods) and Medical Devices. Under her supervision, out of 50 researchers concluded their scientific investigations and she has authored 180 articles in scientific journals, over 12 book chapters. She also has two commercial patents to her name and have taken the management roles in the University, such as being Dean of School of Pharmacy for two mandates (2004-2008 and 2012-2016) and also being Chair of Deliberative Board of FURP – a pharmaceutical industry that manufactures products from the WHO Essential Medicines List and is run by Sao Paulo State Government. Strong scientific skills allied to leadership and management allowed her to establish agreements with internationally prestigious institutions (Universities of Alberta, Lisbon and Bath) as well as some important national scientific and educational institutions.

Dr Kamal Dua, Senior Lecturer, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney (UTS), has a research experience of over 12 years working in the field of drug delivery targeting inflammatory diseases. Dr Dua is also a Node Leader of Drug Delivery Research in the Centre for Inflammation at Centenary Institute/UTS and Senior Research Fellow, the Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), where the targets identified from the research projects are pursued to develop novel formulations as the first step towards translation into clinics. Dr Dua researches in two complementary areas; drug delivery and immunology, specifically addressing how these disciplines can advance one another helping the community to live longer and healthier. This is evidenced by his extensive publication record in reputed journals. Dr. Dua’s research interests focus on harnessing the pharmaceutical potential of modulating critical regulators such as Interleukins and microRNAs and developing new and effective drug delivery formulations for the management of inflammation in chronic airway diseases and cancer.