Nanostructures for Drug Delivery

ISBN-13: 9780323461436 / Angielski / Twarda / 2017 / 1024 str.

Ecaterina Andronescu; Alexandru Mihai Grumezescu

Opis

Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms.

• Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems
• Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area
• Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

Spis treści

1. Therapeutic Nanomaterials: From a Drug Delivery Perspective 2. Core-Shell Drug Carriers: Lipopspmes, Polymersomes, and Colloidosomes 3. Novel nano-carriers based on Graphene and graphene oxide for drug delivery applications 4. Nanostructured nanoparticles for improved drug delivery 5. Design of Functionalised Materials for Use in Micro-Nanoscale Drug Delivery Devices and Smart Patches 6. Niosomes: A novel nano vesicular and an excellent tool for drug delivery system 7. Nanofibrous and Nanoparticles Materials as Drug Delivery Systems 8. Brush Polymer-Based Nanostructures for Drug Delivery 9. Drug delivery systems based on anodic titania nanostructures 10. Redox responsive drug delivery 11. Polymeric micro and nanoparticles for controlled and targeted drug delivery 12. Novel gels: Implications for drug delivery 13. Dosage Form Developments of Nanosuspension Drug Delivery System for Oral Adminstration Route 14. Polymer-based nanocarriers for therapeutic nucleic acids delivery 15. Multifunctional Therapeutic Hybrid Nanocarriers for Targeted and Triggered Drug Delivery: Recent Trends and Future Prospects 16. Lipid Based Nanocarriers for Ocular Drug Delivery 17. Nano platform based new generation vaccine development 18. Pathogen-specific Nucleic Acid Aptamers as Targeting Components of Antibiotic and Gene Delivery Systems 19. Multifunctional Nanosized Emulsions for Theragnosis of Life Threatening Diseases 20. Therapeutic Nanostructures for pulmonary drug delivery 21. Nanostructures in Transdermal Drug Delivery systems 22. Advancement in pulmonary drug delivery systems for treatment of tuberculosis 23. Nanosized devices as antibiotics and antifungals delivery: past, news and outlook 24. Drug delivery mediated by confined nanosystems: structure-activity relations and factors responsible for the efficacy of formulations 25. Therapeutic use of monoclonal antibodies: General aspects and challenges for drug delivery 26. Targeted Drug Delivery Via Polymer Coated Magnetic Nanoparticles 27. Drug Delivery: Advancements and Challenges 28. Stimuli-responsive liposome and control release drug 29. Nanotechnology to Enhance Transdermal Delivery of Hydrophilic Humectants for Improved Skin Care: A Model for Therapeutic Applications 30. Toxicity of nanostructures for drug delivery

O autorze

Ecaterina Andronescu is Professor at UPB, Faculty of Applied Chemistry and Material Science, Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica, Romania. He has been the coordinator for more than 80 research projects with national and international funding and author of more than 330 papers (more than 150 in lSI-ranked journals). Her specific fields of interest are biomaterials, nanomaterials and nanotechnologies; anti-microbial anti-biofilm, and drug delivery systems. Prof. Andronescu has received several honorary titles, including Doctor Honoris Causa - from several universities. She is a member of the Register of Assessors of ARACIS, Commission for Chemistry and Materials Science Founder and President of the Romanian Society of Materials; Founder of the Romanian Society of Biomaterials; Founder and member of the Romanian Society of Ceramics; Founder of the Romanian Society of Chemistry; and Member of the European Society of Ceramics. Dr. Grumezescu is Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science, with a second affiliation to the Faculty of Medical Engineering, at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano and biomaterials, and he is the Editor-in-Chief of three journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, and Biomaterials and Tissue Engineering Bulletin. He also serves as editor or guest editor for several notable journals. Dr. Grumezescu has published 150 peer-reviewed papers, 20 book chapters, 6 co-authored books and 11 edited books.