Nanoscience in Dermatology

ISBN-13: 9780128029268 / Angielski / Miękka / 2016 / 402 str.

Michael Hamblin

Opis

Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine.

• Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology
• Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology
• Coherently structured book written by experts working in the fields covered

Spis treści

1. Anatomy and Function of the Skin Yolanda Gilaberte, Lucia Prieto-Torres, Ievgenia Pastushenko and Ángeles Juarranz

2. Fundamentals of Nanoscience (and Nanotechnology) G. Louis Hornyak and Anil K. Rao

3. An Overview of Nanomaterials in Dermatology Breanne Mordorski, Angelo Landriscina, Adam Friedman

4. Clinical Impact and Patient Safety: The Potential of Microneedles in Changing the Form and Perception of Transdermal Drug Delivery Aaron J. Brady and Ryan F. Donnelly

5. Inorganic nanoparticles for transdermal drug delivery and topical application Min Wang, Srujan Kumar Marepally, Praveen Kumar Vemula and Chenjie Xu

6. Biodegradable, Biocompatible and Bioconjugate Materials as Delivery Agents in Dermatology Fiorenza Rancan

7. Peptide Dendrimers in Delivery of Bioactive Molecules to Skin Jyothsna Menon, Aswathi R Hegde, Harendra S. Parekh and Srinivas Mutalik

8. Insights into Interactions of Gold Nanoparticles with the Skin and Potential Dermatological Applications Nesma El-Sayed, Labiba El-Khourdagui and Marc Schneider

9. Formulation Effects on Topical Nanoparticle Penetration Heather A.E. Benson, Yousuf Mohammed, Jeffrey E. Grice, Michael S. Roberts

10. Nitric Oxide-Releasing Nanoparticles as an Antimicrobial Therapeutic Jamie Rosen, Angelo Landriscina, and Joshua D. Nosanchuk

11. Nanoparticles in the topical treatment of cutaneous Leishmaniasis: gaps, facts and perspectives Socorro Espuelas, Juana Schwartz and Esther Moreno

12. Nanotechnology based nano-bullets in antipsoriatic drug delivery: state of the art Mahfoozur Rahman, Sarwar Beg ,  Firoz Anwar, and Vikas Kumar

13. Nanoparticles for Treatment of atopic dermatitis Mona M. A. Abdel-Mottaleb

14. Challenges and opportunities of nanoparticle-based theranostics in skin cancer Stefania Pizzimenti, Chiara Dianzani, Gian Paolo Zara, Carlo Ferretti, Federica Rossi, Casimiro Luca Gigliotti, Martina Daga, Eric Stefano Ciamporcero, Giovanni Maina and Giuseppina Barrera

15. Nanodelivery of anti-cancer agents in melanoma: encouraging but a long way to go Jiezhong Chen and Xu Dong Zhang

16. Targeted Nanoparticles for Drug Delivery to Melanoma: From Bench to Bedside Jun Li, Yi Zhang and Juan Tao

17. The Potential for Metal Nanoparticle Enhanced Radiotherapy in Dermatology Van L.T. Hoang, Matthew C. Foote, Tarl W. Prow

18. Nanotechnology in Photoprotection Lucy L. Chen, Steven Q. Wang

19. Nanoemulsions to Prevent Photoaging Allesandro Afornali and Márcio Lorencini

20. Decoupling hazard from risk in using sunscreens containing metal oxide nanoparticles Megan J. Osmond McLeod

21. Nanoparticle Oxygen Sensing in Skin Zongxi Li and Conor L. Evans

22. Investigating the intracellular dynamics of Hypericin loaded nanoparticles and polyvinylpyrrolidone-Hypericin by image correlation spectroscopy Rozhin Penjweini, Sarah Deville, Anitha Ethirajan and Marcel Ameloot

23. Accelerated Wound Healing Using Nanoparticles Ee Teng Goh, Georgia Kirby, Jayakumar Rajadas, Xing-Jie Liang and Aaron Tan

24. Migration through naturally existing barriers and distribution of QDs in the skin Ricardas Rotomskis

25. Nanomedicines for the Eye: Current Status and Future Development Anthony A. Attama, Joy N. Reginald-Opara, Emmanuel M. Uronnachi and Ebele B. Onuigbo

26. Bioinspired Nano-Substrates for Skin Regeneration Shima Tavakol, Sasan Jalili-Firoozinezhad, Omid Mashinchian and Morteza Mahmoudi

27. Imaging Nanoparticle Skin Penetration in Humans Lynlee L. Lin, Miko Yamada and Tarl W. Prow

28. EGF-loaded Nanofibers for Skin Tissue Engineering Mohammad Norouzi and Masoud Soleimani

O autorze

Michael R Hamblin Ph.D. is a Principal Investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital, an Associate Professor of Dermatology at Harvard Medical School and is a member of the affiliated faculty of the Harvard-MIT Division of Health Science and Technology. He was trained as a synthetic organic chemist and received his PhD from Trent University in England. His research interests lie in the areas of photodynamic therapy (PDT) for infections, cancer, and heart disease and in low-level light therapy (LLLT) for wound healing, arthritis, traumatic brain injury and hair-regrowth. He directs a laboratory of around a sixteen post-doctoral fellows, visiting scientists and graduate students. His research program is supported by NIH, CDMRP, USAFOSR and CIMIT among other funding agencies. He has published 252 peer-reviewed articles, over 150 conference proceedings, book chapters and International abstracts and holds 8 patents. He is Associate Editor for 7 journals, on the editorial board of a further 12 journals and serves on NIH Study Sections. For the past 9 years Dr Hamblin has chaired an annual conference at SPIE Photonics West entitled "Mechanisms for low level light therapy" and he has edited the 9 proceedings volumes together with four other major textbooks on PDT and photomedicine. He has several other book projects in progress at various stages of completion. In 2011 Dr Hamblin was honored by election as a Fellow of SPIE. Pinar Avci, MD is a Research Fellow in Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School Department of Dermatology, Boston USA. She received her MD degree in General Medicine from Semmelweis University, and is currently pursuing her PhD in Department of Dermatology, Venereology and Dermato-oncology, Semmelweis University, Budapest, Hungary. She is currently conducting research in the area of Photodynamic therapy (PDT) - a localized approach for treatment of cancer and infections and its effects in developing anti-tumor immunity. In 2004, Dr Prow earned his Ph.D. from the University of Texas in the field of Nanomedicine. He then completed his T32 funded post-doc at the Wilmer Eye Institute at The Johns Hopkins Hospital and was faculty there until he relocated to the University of Queensland in Brisbane, Australia in 2007. In 2011 Dr Prow became the Deputy Director of the Dermatology Research Centre. In 2015, Dr Prow was promoted to Associate Professor within the University of Queensland's School of Medicine. He leads a NHMRC and ARC funded team that focuses on drug delivery, diagnostics and imaging in the context of dermatology.