Nanomedicines for Brain Drug Delivery

ISBN-13: 9781071608401 / Angielski / Miękka / 2021

Opis

This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Thorough and cutting-edge, Nanomedicines for Brain Drug Delivery is a valuable resource that will help researchers guide and advance the field of nanomedicines for the brain and nervous system.

Spis treści

Series Preface…
Preface…
Table of Contents …
Contributing Authors…

1. Biodegradable Polymeric Nanoparticles for Brain-Targeted Drug Delivery
Kristian Kempe and Joseph A. Nicolazzo

2. Liposomes as Brain Targeted Delivery Systems
Francesco Lai, Michele Schlich, Chiara Sinico, and Anna M. Fadda

3. Nanofibres and Nanostructured Scaffolds for Nervous System Lesions
Jose L. Gerardo Nava, Jonas C. Rose, Haktan Altinova, Paul D. Dalton, Laura DeLaporte, and Gary A. Brook

4. Self-Assembling Peptide Nanofibrous Scaffolds in Central Nervous System Lesions 
Zhang Na, Liumin He, and Wu Wutian

5. The Use of Peptide and Protein Vectors to Cross the Blood Brain Barrier for the Delivery of Therapeutic Concentration of Biologics
Mei Mei Tian and Reinhard Gabathuler

6. Inorganic Nanoparticles and Their Strategies to Enhance Brain Drug Delivery
Eduardo Gallardo-Toledo, Carolina Velasco-Aguirre, and Marcelo Javier Kogan

7. Magnetic Nanoparticles as Delivery Systems to Penetrate the Blood Brain Barrier 
Joan Estelrich and Maria Antònia Busquets

8. Nose-to-Brain Drug Delivery Enabled by Nanocarriers
Zachary Warnken, Yang Lu, Hugh D. C. Smyth, and Robert O. Williams III 

9. In Vitro Models of Central Nervous System Barriers for Blood Brain Barrier Permeation Studies 
Rahul Dev Jayant, Sneham Tiwari, Venkata Atluri, Ajeet Kaushik, Rahul Mittal, Abhijeet Joshi, and Madhavan Nair

10. Safety and Nanotoxicity Aspects of Nanomedicines for Brain-Targeted Drug Delivery 
Johanna Catalan-Figueroa and Javier O. Morales

Subject Index List…