Nanomedicine and the Nervous System

ISBN-13: 9781578087280 / Angielski / Twarda / 2012 / 380 str.

Colin R. Martin;Victor R. Preedy;Ross J. Hunter

Opis

The nanosciences encompass a variety of technologies ranging from particles to networks and nanostructures. Nanoparticles can be suitable carriers of therapeutic agents, and nanostructures provide suitable platforms and scaffolds for sub-micro bioengineering. This book focuses on nanomedicine and nanotechnology as applied to the nervous system and the brain. It covers nanoparticle-based immunoassays, nanofiber microbrush arrays, nanoelectrodes, protein nanoassemblies, nanoparticles-assisted imaging, nanomaterials, and ion channels. Additional topics include stem cell imaging, neuronal performance, treatment of stroke and spinal cord injury, and lipid nanostructures.

Spis treści

General Aspects: Safety of Carbon Nanotubes for Neuronal Tissue. Nanoparticle-based Immunoassays and their Applications in Nervous System Biomarker Detection, Electrical Stimulation of Brain Tissue with Carbon Nanofiber Microbrush Arrays, Nanoelectrode Arrays for Monitoring and Modulating Nervous System Electrical and Chemical Activity. Probing Protein Nanoassemblies in Neurodegenerative Disease. Nanoparticle-assisted Laser Desorption/ionization (nano-PALDI)-based Imaging Mass Spectrometry (IMS) and its Application to Brain Sciences. Nanomaterials and Ion Channels: Observed Effects and Possible Mechanisms. Biomolecular Engineering for the Regulation of Alpha-synuclein Nanostructure toward the Development of Alpha-synuclein Targeting Nanomedicine. Nanomaterials for Stem Cell Imaging in the Central Nervous System. Carbon Nanotubes and Neuronal Performance.Therapeutics: Nanotechnologies for Treatment of Stroke and Spinal Cord Injury. Delivering siRNA Using Nanoparticles to the Central Nervous System. Targeting Drug Delivery to the Brain via Transferrin Anchored Nanoparticles. Therapeutic-loaded Lipid Nanostructures and Brain Diseases. Nanocarriers for the Treatment of Brain Tumours. Electrospinning of Nanofibres for Repair of the Injured Peripheral Nervous System. Bridging the Gap for Regeneration after CNS Injury by Nanofiber Scaffolds: Use of SAPNS for Traumatic Brain and Spinal Cord Injury. Nanoparticle-iron Chelator Conjugates as Multifunctional Disease-modifying Drugs for Prevention and Treatment of Alzheimer’s Disease. The Pharmacological and Toxicological Profiles of Carbon Nanotubes as Drug Carriers toward Central Nervous System.

O autorze

Martin, Colin R.; Preedy, Victor R.; Hunter, Ross J.