Part 1. Introduction to hyperthermia 1. Basic concepts of hyperthermia 2. Cellular response to heat stress 3. Hyperthermia for combined cancer therapy 4. Current status of clinical trials in hyperthermia 5. Hyperthermia at the nanoscale - why nanomaterials? 6. Fundamentals of magnetic and optical hyperthermia
Part 2. Magnetic hyperthermia 1. Interaction of magnetic nanoparticles with alternating magnetic fields (Q. Pankhurst) 2. Mechanisms of magnetic heat generation (Q. Pankhurst, T. Pellegrino) 3. Design and synthesis of MNPs for hyperthermia applications 4. In vitro magnetic hyperthermia: influence of subcellular localization of magnetic nanoparticles on their heating efficiency 5. Sub-lethal magnetic hyperthermia: cellular response to mild heat stress 6. Current status of in vivo application of magnetic hyperthermia for cancer treatment
Part 3. Optical hyperthermia 1. Principles of optical hyperthermia (J. C. Bischof) 2. Gold plasmonic nanoparticles as photothermal therapy agents 3. Graphene - based nanomaterials for optical hyperthermia applications 4. Novel nanomaterials for photothermal therapy 5. In vitro applications: mechanism of cell death induced by optical hyperthermia 6. Current status of in vivo photothermal therapy applications
Part 4. Synergistic modalities 1. Synergistic effect of dual magnetic/optical heating 2. Hybrid magnetic-plasmonic nanomaterials for bimodal hyperthermia 3. Smart multifunctional magnetic nanoparticles for combined drug delivery and magnetic hyperthermia