Nanocarrier Technologies: Frontiers of Nanotherapy

ISBN-13: 9789048172627 / Angielski / Miękka / 2010 / 226 str.

M. Reza Mozafari

Opis

Nanobiotechnology is one of the key technologies of the 21^st century. It is a combination of nanoscience and biotechnology and covers areas ranging from gene transfer and nanoencapsulation to food technology. Nanocarriers are a leading nanobiotechnology tool with the ability to provide protection, site-specific delivery, enhanced bioavailability and controlled release of pharmaceuticals, genetic material, imaging agents, nutraceuticals and cosmetics to name a few. For this reason, the study of nanocarriers, their properties and applications has attracted a great deal of interest over recent years. Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies including their preparation methods, evaluation of their safety and efficiency, their interaction with biologicals and their application in biotechnology, drug delivery, gene therapy and food technology areas.

Spis treści

Contributing Authors; Preface; Foreword; Acknowledgments; Chapter 1: Bioactive Entrapment and Targeting Using Nanocarrier Technologies: An Introduction 1 M.R. Mozafari; Chapter 2: Archaeosomes as Drug and Vaccine Nanodelivery Systems 17 G.B. Patel and W. Chen; Chapter 3: Solid Lipid Nanoparticles 41 A. Saupe and T. Rades; Chapter 4: Hydrotropic Nanocarriers for Poorly Soluble Drugs 51 T. Ooya, S.C. Lee, K.M. Huh and K. Park; Chapter 5: Biomimetic Approach to Drug Delivery and 75 E.T. Baran and R.L. Reis Optimization of Nanocarrier Systems viii Contents; Chapter 6: A Role for Prebiotics in Controlled Drug Delivery 87 A. Awati and P.J. Moughan; Chapter 7: Recent Advances in the Delivery of Food-Derived Bioactives and Drugs Using Microemulsions 95 J. Flanagan and H. Singh; Chapter 8: Pharmacokinetic Modulation with Particulate Drug Formulations 113 M. Langner and A. Kozubek; Chapter 9: Synthetic Vectors for Genetic Drug Delivery 139 P. Wyrozumska, K. Stebelska, M. Grzybek and A.F. Sikorski; Chapter 10: Dicationic DEGA-Based Lipid Systems for Gene Transfer and Delivery: Supramolecular Structure and Activity 175 A.S. Elkady and R.I. Zhdanov; Chapter 11: The Role of Liposomal Antioxidants in Oxidative Stress 191 Z.E. Suntres and A. Omri; Chapter 12: Interaction of Dendrimers with Model Lipid Membranes Assessed by DSC and Raman Spectroscopy K. Gardikis, S. Hatziantoniou, K. Viras, M. Wagner and C. Demetzos; Index.