Multifunctional And Targeted Theranostic Nanomedicines: Formulation, Design And Applications

ISBN-13: 9789819905379 / Angielski / Twarda / 2023

Keerti Jain; N. K. Jain

Opis

This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use.
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Spis treści

Chapter 1_Functionalized Targeted Theranostic Nanomedicines. -Chapter 2_Designing of Smartly Functionalized Theranostic Nanomedicines. -Chapter 3_Functionalized Vesicular Carriers and Theranostic Applications. -Chapter 4_Theranostic Applications of Functionalized Polymeric Nanoparticles. -Chapter 5_Functionalized Metallic Nanoparticles: Theranostic Applications.-Chapter 6_Functionalized Lipidic Nanoparticles: Smartly Engineered Lipidic Theranostic Nanomedicines. -Chapter 7_ Functionalized Nanoemulsions: Could be a Promising Approach for Theranostic Applications. -Chapter 8_Functionalized Hyperbranched polymers: Promising candidates for Theranostic Applications. -Chapter 9_Functionalized Carbon Nanotubes, Graphene oxide, Fullerenes, and Nanodiamonds: Emerging Theranostic Nanomedicines. -Chapter 10_Functionalized Quantum Dots and Theranostic Applications. -Chapter 11_Functionalized Nanogels and Theranostic Applications. -Chapter 12_Theranostic Applications of Functionalized Exosomes. -Chapter 13_Theranostic Applications of Functionalized Polymeric Micelles. -Chapter 14_Functionalized Nanocrystals and Theranostic Applications. -Chapter 15_ Theranostic Applications of Functionalized Magnetic Nanoparticles. -Chapter 16_Functionalized Mesoporous Silica Based Nanoparticles for Theranostic Applications. -Chapter 17_Challenges and Opportunities in the Development of Functionalized Theranostic Nanomedicines​

O autorze

Dr. Keerti Jain, Assistant Professor, Department of Pharmaceutics, at National Institute of Pharmaceutical Education and Research (NIPER) – Raebareli, India, earned her M. Pharm. and Doctorate from the Department of Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar. She did her Post Doctorate from M. S. University of Vadodara, India, as SERB-National Post-Doctoral Fellow. She has more than 12 years of research experience on Nanomedicine based drug delivery systems and supervised M. Pharm., M.S. Pharm., Pharm.D. and Ph.D. students for their research work. She is the author of more than 70 international publications in peer reviewed-high impact factor journals.

Dr. Jain has filed five patents from her innovative research and received funding for research projects from ICMR and SERB, New Delhi. She has been awarded for her research work with prestigious ICMR – Shakuntala Amir Chand Award, Most Innovative Idea Award, SPER-WF Young Scientist Award 2022, SERB – NPDF, Fellowship for the training of young scientist (MPCST), Travel grant award (INSA), and International Travel Fellowship (ICMR and DBT). She has been enlisted among World’s Top 2% Scientists consecutively for three years from 2020 to 2022 in the list created by Stanford University, USA.

Prof. N. K. Jain is an internationally renowned academician and researcher. He has worked as Professor and Principal, College of Pharmacy, Nasik; Professor and Head, Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar; Principal, College of Pharmacy, New Delhi; Visiting Professor, Dubai Pharmacy College, Dubai (UAE); and Head, Pharmacy Department, Delhi University. After his superannuation, Prof. Jain was a Director, ISF College of Pharmacy, Moga, Punjab, India) as Emeritus Fellow (U.G.C.) at Rajiv Gandhi Technological University, Bhopal, M.P., India. He has published more than 480 research articles in journals of high repute. He has been a reviewer for several international and national research journals. He is the recipient of several awards, notably, IDMA Research Award in Industrial Pharmacy Dr. (Mrs.) ManjuSree Pal Memorial Award of the Association of Pharmaceutical Teachers of India for Best Pharmaceutical Scientist, and Schroff Memorial National Award for his outstanding contributions as an author, academician, and scientist by the Indian Hospital Pharmacists’ Association, and was elected for the prestigious and Indian Association of Pharmaceutical Scientists and Technologists (IAPST) Lifetime Achievement Award conferred at the 5th IAPST Annual Convention. Most recently he was conferred the prestigious “APTI Shri Bhojraj Panjamool Lifetime Achievement Award” at 25^th APTICON, JSS Mysore, India by the Association of Pharmaceutical Teachers of India on 2nd Sept 22.

According to a recent ranking announced by the Stanford University Scientists [based on a database of over 1 lakh top scientists of the world on the basis of standardized citation indicators], Prof. N.K. Jain is included in top 2% scientists in the world in the area of Pharmacology and Pharmacy, consecutively for 3 years.