Moyamoya Disease: Current Knowledge and Future Perspectives

ISBN-13: 9789813364035 / Angielski / Twarda / 2021 / 341 str.

Satoshi Kuroda

Spis treści

Part I. Concept of Moyamoya Disease 1 History of Disease Entity & Diagnosis Criteria 2 Moyamoya Syndrome 3 Unilateral Moyamoya Disease: A Distinct Entity? Part II. Genetic Aspect of Moyamoya Disease 4 RNF213 as Susceptibility Gene 5 RNF213 and clinical feature 6 RNF213 Variant as a Biomarker of Cerebrovascular Disease  Part III. Pathophysiology of Moyamoya Disease 7 TIA & Headache in Pediatric Moyamoya Disease 8 Ischemic stroke 9 Hemorrhagic Stroke and the Japan Adult Moyamoya Trial 10 Cognitive Function in Pediatric Moyamoya Disease 11 Cognitive Dysfunction in Adults 12 Asymptomatic Moyamoya Disease Part IV. Update on Neuroradiology in Moyamoya Disease 13 Periventricular Anastomosis 14 Arterial Shrinkage 15 Disease progression 16 Postoperative hyperperfusion 17 Postoperative FLAIR Imaging Changes Part V. Real World of Surgical Revascularization for Moyamoya Disease 18 Overview of Surgical Revascularization and Long-term Outcome in Japan 19 Perioperative complications  20 Long-term Outcome in Europe 21 Long Term Outcomes in USA 22 Long-term Outcome in China 23 Long-term outcome of revascularization surgery for moyamoya disease in Korea 24 Indirect bypass surgery for moyamoya disease 25 Direct/combined bypass surgery 26 Special Considerations—Infants 27 Special Considerations – Elderly

O autorze

Professor Satoshi Kuroda, MD, PhD, IFAANS

Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science,

University of Toyama,

Toyama, Japan

skuroda@med.u-toyama.ac.jp

Blurb

This book brings together the latest knowledge on moyamoya disease, covering diagnostic criteria, status as a disease entity, genetic aspects, pathophysiology, novel neuroradiological findings, and surgical therapy. Information is also provided on recent basic and clinical research with the aim of identifying future perspectives on the disease.

Since moyamoya disease was first reported in an English language article more than 50 years ago, our understanding of it has advanced considerably. Genetic and radiological analysis has delivered novel insights, and the latest multicenter studies are changing routine diagnosis and surgical therapy. The gene encoding the ring finger protein 213 (RNF213) has been identified as a susceptibility gene for moyamoya disease. Indications and procedures for surgical revascularization have been revised, with resultant improvements in outcomes, and studies performed over the past decade have provided new knowledge on the neuroradiological findings before and after surgery.

In describing these advances, this book will be an invaluable asset for all general physicians, pediatricians, neurologists, radiologists, and neurosurgeons who care for patients with moyamoya disease across the world.